Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 known ✓ | P03372 | 1/20 | 0.48 |
| ▸ | KMO | O15229 | 1/20 | 0.56 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | DHODH | Q02127 | 2/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 2/20 | 0.44 |
| ▸ | RXRB | P28702 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | RXRG | P48443 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL28772928 | 1.00 | KMO (0.56) | KMOACMSDMAPTSMN1; SMN2MEN1 | |
| Acetone SCHEMBL18784619 | 0.91 | KMO (0.52) | KMOACMSDMAPTSMN1; SMN2MEN1 | |
| Pyruvate SCHEMBL27990027 | 0.89 | KMO (0.52) | KMOACMSDMAPTSMN1; SMN2MEN1 | |
| Bicarbonate SCHEMBL11165825 | 0.88 | KMO (0.61) | KMOACMSDMEN1ESR1KMT2A | |
| Acetic Acid SCHEMBL9680398 | 0.87 | KMO (0.45) | KMOACMSDMAPTSMN1; SMN2MEN1 | |
| Acetamide SCHEMBL1259199 | 0.86 | DHODH (0.48) | KMOACMSDMAPTMEN1ESR1 | |
| Acetic Acid SCHEMBL27559163 | 0.85 | SMN1; SMN2 (0.64) | KMOMAPTSMN1; SMN2MEN1KMT2A | |
| Oxalic Acid SCHEMBL27820733 | 0.85 | KMO (0.58) | KMOACMSDMEN1ESR1KMT2A | |
| Acetophenone SCHEMBL27984785 | 0.83 | MAPT (0.68) | KMOMAPTSMN1; SMN2MEN1KMT2A | |
| Bicarbonate SCHEMBL9702180 | 0.82 | KMO (0.70) | KMOACMSDMEN1ESR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 137 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117046304-A | Acid-catalyzed cross-linked high-flux acid-resistant nanofiltration membrane and preparation method thereof | 宁波日新恒力科技有限公司 | 2023-11-14 | — | — | CN | claimed |
| EP-3141284-B1 | METHOD OF STRAIGHTENING KERATINOUS FIBERS USING HEATING MEANS AND AN ACID DERIVATIVE | OREAL (FR) | 2019-08-28 | — | — | EP | claimed |
| EP-2029237-B1 | METHOD FOR STRAIGHTENING KERATINOUS FIBERS USING HEATING MEANS AND AN ACID DERIVATIVE | ORÉAL L (FR) | 2016-10-12 | — | — | EP | claimed |
| US-20160074296-A1 | METHOD FOR STRAIGHTENING HUMAN HAIR FIBERS USING HEATING MEANS AND AN a-HYDROXY ACID DERIVATIVE | L'OREAL (FR) | 2016-03-17 | — | — | US | claimed |
| US-20130139844-A1 | METHOD FOR STRAIGHTENING HUMAN HAIR FIBERS USING HEATING MEANS AND AN ¤-HYDROXY ACID DERIVATIVE | L'OREAL S.A. (FR) | 2013-06-06 | — | — | US | claimed |
| CN-102822166-A | Processes for the preparation of 5 - lipooxygenase activating protein inhibitors and their intermediates | GLAXO GROUP LTD | 2012-12-12 | — | — | CN | claimed |
| CN-102070576-B | 1-indanone-3-acetic acid compound as well as preparation method and application of 1-indanone-3-acetic acid compound | UNIV SICHUAN | 2012-11-28 | — | — | CN | claimed |
| CN-102417497-A | Preparation method of optically active 1-indanone-3-acetic acid compound | UNIV SICHUAN | 2012-04-18 | — | — | CN | claimed |
| CN-102381961-A | 3-phenyl glutaric acid compound, preparation method and purpose thereof | UNIV SICHUAN | 2012-03-21 | — | — | CN | claimed |
| US-20110136168-A1 | PROCESS FOR PRODUCTION OF NON-NATURAL PROTEIN HAVING ESTER BOND THEREIN | RIKEN (JP) | 2011-06-09 | — | — | US | claimed |
| CN-102070576-A | 1-indanone-3-acetic acid compound as well as preparation method and application of 1-indanone-3-acetic acid compound | UNIV SICHUAN | 2011-05-25 | — | — | CN | claimed |
| US-20100300471-A1 | METHOD FOR STRAIGHTENING KERATINOUS FIBERS USING HEATING MEANS AND AN ACID DERIVATIVE | L'OREAL S.A. (FR) | 2010-12-02 | — | — | US | claimed |
| CN-1893910-A | Cyclic siloxane compositions for active ingredient release | GEN ELECTRIC (US) | 2007-01-10 | — | — | CN | claimed |
| WO-2024122393-A1 | COMPOSITION FOR IMPROVED STRAIGHTENING OF KERATIN FIBERS | L'OREAL (FR) | 2024-06-13 | — | — | WO | disclosed |
| CN-117225384-B | Composite material capable of efficiently adsorbing formaldehyde and noble metal as well as preparation method and application thereof | 天津得瑞丰凯新材料科技有限公司 | 2024-02-09 | — | — | CN | disclosed |
| US-20240010610-A1 | COMPOUNDS FOR TREATING SEGMENTAL PROGEROID SYNDROMES | PROGELIFE (FR) | 2024-01-11 | — | — | US | disclosed |
| US-4393178-A | REACTED WITH IONIZABLE METAL SALT OF AROMATIC COMPOUND | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1983-07-12 | — | — | US | disclosed |
| US-4368288-A | REACTION PRODUCT WITH IONIZABLE ORGANIC METAL SALT | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1983-01-11 | — | — | US | disclosed |
| US-4305864-A | IONIZABLE METAL SALT NUCLEATING AGENT | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1981-12-15 | — | — | US | disclosed |
| EP-0021648-A1 | Fast crystallising polyester compositions | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1981-01-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100300471-A1 | METHOD FOR STRAIGHTENING KERATINOUS FIBERS USING HEATING MEANS AND AN ACID DERIVATIVE | KRT18, KLK5, HOGA1 | ESR1 4517/4885KMO 99/4885ACMSD 819/4885 |
| US-20160074296-A1 | METHOD FOR STRAIGHTENING HUMAN HAIR FIBERS USING HEATING MEANS AND AN a-HYDROXY ACID DERIVATIVE | KRT18, HOGA1, CYP27B1 | ESR1 4532/4885KMO 126/4885ACMSD 505/4885 |
| US-20130139844-A1 | METHOD FOR STRAIGHTENING HUMAN HAIR FIBERS USING HEATING MEANS AND AN ¤-HYDROXY ACID DERIVATIVE | KRT18, HOGA1, CYP27B1 | ESR1 4490/4885KMO 146/4885ACMSD 825/4885 |
| US-20240010610-A1 | COMPOUNDS FOR TREATING SEGMENTAL PROGEROID SYNDROMES | LMNA, LMNB2, LMNB1 | ESR1 4842/4885KMO 4214/4885ACMSD 3411/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.