Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.48 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.48 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.48 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.48 |
| ▸ | CYP2A7 | P20853 | 1/20 | 0.48 |
| ▸ | CYP3A7 | P24462 | 1/20 | 0.48 |
| ▸ | CYP2F1 | P24903 | 1/20 | 0.48 |
| ▸ | CYP2C18 | P33260 | 1/20 | 0.48 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.48 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.48 |
| ▸ | CYP4F8 | P98187 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27693954 | 0.85 | CYP2C19 (0.48) | ALDH1A1CYP2C19CYP3A4CYP1A1CYP1A2 | |
| Acetone SCHEMBL18784619 | 0.84 | KMO (0.52) | CYP2C19CYP3A4CYP1A1CYP1A2CYP2E1 | |
| Biphenyl SCHEMBL27819830 | 0.82 | SMN1; SMN2 (0.56) | ALDH1A1CYP2C19KMT2AMAPT | |
| Benzene SCHEMBL28772928 | 0.81 | KMO (0.56) | LMNAGAAKMOMEN1ESR1 | |
| Acetic Acid SCHEMBL734741 | 0.81 | KMO (0.56) | LMNAGAAKMOMEN1ESR1 | |
| SCHEMBL3028133 | 0.80 | KMO (0.45) | ALDH1A1CYP2C19CYP1A2KMOMEN1 | |
| Acetamide SCHEMBL1259199 | 0.79 | DHODH (0.48) | CYP2C19CYP3A4CYP1A1CYP1A2CYP2E1 | |
| SCHEMBL9566050 | 0.78 | KMO (0.43) | ALDH1A1CYP2C19CYP1A2KMOMEN1 | |
| M-Xylene SCHEMBL21296279 | 0.78 | LMNA (0.61) | ALDH1A1CYP3A4LMNAGAAMEN1 | |
| Ethyl Acetate SCHEMBL8096818 | 0.78 | ALDH1A1 (0.58) | ALDH1A1CYP1A2LMNAGAACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0804468-B1 | METHOD OF MAKING AN OMEGA-FUNCTIONALIZED AMINO ACID DERIVATIVE | DEVELOGEN ISRAEL LTD (IL) | 2007-04-25 | — | — | EP | disclosed |
| US-7084244-B2 | Conformationally constrained backbone cyclized peptide analogs | DEVELOGEN ISRAEL LTD. (IL) | 2006-08-01 | — | — | US | disclosed |
| WO-2006051312-A1 | GASTRIN AND CHOLECYSTOKININ RECEPTOR LIGANDS | JAMES BLACK FOUNDATION LIMITED (GB) | 2006-05-18 | — | — | WO | disclosed |
| US-20030144186-A1 | Conformationally constrained backbone cyclized peptide analogs | DEVELOGEN ISRAEL LTD. (IL) | 2003-07-31 | — | — | US | disclosed |
| US-6407059-B1 | SOMATOSTATIN-TYPE DRUG | PEPTOR LIMITED (IL) | 2002-06-18 | — | — | US | disclosed |
| US-6265375-B1 | Conformationally constrained backbone cyclized peptide analogs | YISSUM RESEARCH DEVELOPMENT CO. OF THE HEBREW UNIVERSITY (IL) | 2001-07-24 | — | — | US | disclosed |
| US-5874529-A | BRADYKININ ANTAGONIST | PEPTOR LTD. (IL) | 1999-02-23 | — | — | US | disclosed |
| US-5811392-A | BRADYKININ ANTAGONISTS; SOMATOSTATIN ANALOGS | YISSUM RESEARCH DEVELOPMENT CO. OF THE HEBREW UNIVERSITY (IL) | 1998-09-22 | — | — | US | disclosed |
| EP-0804468-A1 | CONFORMATIONALLY CONSTRAINED BACKBONE CYCLIZED PEPTIDE ANALOG | PEPTOR LTD (IL) | 1997-11-05 | — | — | EP | disclosed |
| WO-1995033765-A1 | CONFORMATIONALLY CONSTRAINED BACKBONE CYCLIZED PEPTIDE ANALOG | PEPTOR LTD. (IL) | 1995-12-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030144186-A1 | Conformationally constrained backbone cyclized peptide analogs | VIP, BDKRB1, BDKRB2 | ALDH1A1 4862/4885CYP2C19 3991/4885CYP3A4 4403/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.