Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR4 | P46093 | 10/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30299386 | 0.87 | SIGMAR1 (0.40) | KCNH2HRH3LMNAHIF1ACYP3A4 | |
| SCHEMBL30299400 | 0.86 | LTA4H (0.47) | KCNH2HRH3LMNAHIF1ACYP3A4 | |
| SCHEMBL30299272 | 0.85 | LTA4H (0.46) | KCNH2HRH3LMNAHIF1ACYP3A4 | |
| SCHEMBL30299395 | 0.83 | TSHR (0.38) | KCNH2LMNAHIF1ACYP3A4GAA | |
| SCHEMBL30299339 | 0.83 | HRH3 (0.39) | HRH3LMNAALDH1A1KDM4E | |
| SCHEMBL30299374 | 0.81 | SMN1; SMN2 (0.35) | GPR4LMNAGAACHRM3PKM | |
| SCHEMBL30299348 | 0.78 | GPR4 (0.42) | GPR4HRH3LMNAOPRM1OPRK1 | |
| SCHEMBL30299399 | 0.78 | GPR4 (0.37) | GPR4LMNAOPRM1SIGMAR1OPRK1 | |
| SCHEMBL30299358 | 0.78 | GPR4 (0.43) | GPR4HRH3OPRM1OPRK1ALDH1A1 | |
| SCHEMBL30299397 | 0.77 | ALDH1A1 (0.33) | HRH3HTR2AHRH1HTR2BSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916344-A | AXL inhibitors for antiviral therapy | 卑尔根生物股份公司 | 2023-04-04 | — | — | CN | disclosed |