Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 13/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.39 |
| ▸ | PARP1 | P09874 | 2/20 | 0.38 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30299315 | 0.86 | LMNA (0.52) | HRH3PARP1LMNAKDM4EALDH1A1 | |
| SCHEMBL30299394 | 0.83 | GPR4 (0.43) | HRH3LMNAKDM4EALDH1A1 | |
| SCHEMBL30299269 | 0.79 | MEN1 (0.45) | HRH3KDM4EALDH1A1 | |
| SCHEMBL30299294 | 0.77 | L3MBTL3 (0.47) | HRH3KDM4EALDH1A1 | |
| SCHEMBL1126070 | 0.73 | LMNA (0.66) | HRH3LMNAKDM4EALDH1A1TDP1 | |
| SCHEMBL30299386 | 0.69 | SIGMAR1 (0.40) | HRH3LMNAKDM4EALDH1A1TDP1 | |
| Water SCHEMBL27827706 | 0.69 | HRH3 (0.51) | HRH3LMNAKDM4EALDH1A1TDP1 | |
| SCHEMBL14983598 | 0.68 | SIGMAR1 (0.61) | HRH3LMNAKDM4EALDH1A1 | |
| SCHEMBL10263723 | 0.68 | POLB (0.58) | HRH3KDM4EALDH1A1TDP1 | |
| SCHEMBL10261035 | 0.68 | ALDH1A1 (0.65) | HRH3LMNAKDM4EALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116075303-A | Method of selecting patients treated with a combination of an AXL inhibitor and an immune checkpoint modulator | 卑尔根生物股份公司 | 2023-05-05 | — | — | CN | disclosed |
| CN-115916344-A | AXL inhibitors for antiviral therapy | 卑尔根生物股份公司 | 2023-04-04 | — | — | CN | disclosed |