Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | CYP21A2 | P08686 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP4 | P49662 | 1/20 | 0.34 |
| ▸ | CASP5 | P51878 | 1/20 | 0.34 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30299398 | 0.92 | OPRM1 (0.34) | CASP1CASP4CASP5TRPC5OPRM1 | |
| SCHEMBL30299387 | 0.86 | OPRM1 (0.31) | CASP1CASP4CASP5OPRM1OPRK1 | |
| SCHEMBL30299377 | 0.84 | PDE3B (0.34) | ALDH1A1LMNAMAPTMAPK1GFER | |
| SCHEMBL30299371 | 0.82 | ALDH1A1 (0.43) | ALDH1A1LMNAMAPTMAPK1GFER | |
| SCHEMBL30299369 | 0.82 | AXL (0.37) | HTR1AALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL30090687 | 0.81 | AXL (0.38) | OPRM1OPRL1ALDH1A1LMNAMAPT | |
| SCHEMBL29929683 | 0.80 | AXL (0.40) | ALDH1A1LMNA | |
| SCHEMBL30090537 | 0.80 | TNIK (0.36) | — | |
| SCHEMBL29928123 | 0.79 | AXL (0.39) | ALDH1A1 | |
| SCHEMBL30299346 | 0.79 | RET (0.36) | CASP1CASP4CASP5TRPC5DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116075303-A | Method of selecting patients treated with a combination of an AXL inhibitor and an immune checkpoint modulator | 卑尔根生物股份公司 | 2023-05-05 | — | — | CN | disclosed |
| CN-115916344-A | AXL inhibitors for antiviral therapy | 卑尔根生物股份公司 | 2023-04-04 | — | — | CN | disclosed |