Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 3/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.34 |
| ▸ | CDC42BPA | Q5VT25 | 3/20 | 0.34 |
| ▸ | CDC42BPB | Q9Y5S2 | 3/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.33 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
| ▸ | AXL | P30530 | 2/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30299325 | 0.98 | ROCK2 (0.32) | ROCK2ROCK1CDC42BPACDC42BPBPIK3CD | |
| SCHEMBL30299345 | 0.92 | AXL (0.38) | CSF1RCDK4CDK6ALDH1A1SMN1; SMN2 | |
| SCHEMBL30299298 | 0.92 | ALDH1A1 (0.32) | ALDH1A1SMN1; SMN2HRH3AXL | |
| SCHEMBL29929683 | 0.89 | AXL (0.40) | CSF1RCDK4CDK6ALDH1A1SMN1; SMN2 | |
| SCHEMBL29928123 | 0.88 | AXL (0.39) | CSF1RCDK4CDK6ALDH1A1SMN1; SMN2 | |
| SCHEMBL30299369 | 0.87 | AXL (0.37) | KDM4EALDH1A1SMN1; SMN2HRH3AXL | |
| SCHEMBL30090687 | 0.86 | AXL (0.38) | KDM4EALDH1A1AXLKMT2A | |
| SCHEMBL30299381 | 0.82 | IP6K1 (0.32) | — | |
| SCHEMBL30299368 | 0.80 | GAA (0.38) | KDM4EHTTALDH1A1SMN1; SMN2AXL | |
| SCHEMBL30299377 | 0.80 | PDE3B (0.34) | ALDH1A1SMN1; SMN2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116075303-A | Method of selecting patients treated with a combination of an AXL inhibitor and an immune checkpoint modulator | 卑尔根生物股份公司 | 2023-05-05 | — | — | CN | disclosed |
| CN-115916344-A | AXL inhibitors for antiviral therapy | 卑尔根生物股份公司 | 2023-04-04 | — | — | CN | disclosed |