Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.36 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.33 |
| ▸ | NPY2R | P49146 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.33 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | FLT1 | P17948 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 2/20 | 0.32 |
| ▸ | ROS1 | P08922 | 2/20 | 0.32 |
| ▸ | FLT3 | P36888 | 2/20 | 0.32 |
| ▸ | EML4 | Q9HC35 | 2/20 | 0.32 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.32 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29929683 | 0.87 | AXL (0.40) | L3MBTL3L3MBTL1HRH3NPY2RMBTD1 | |
| SCHEMBL29928123 | 0.86 | AXL (0.39) | L3MBTL3L3MBTL1HRH3NPY2R | |
| SCHEMBL30299323 | 0.85 | NPY2R (0.41) | L3MBTL3L3MBTL1HRH3NPY2RMBTD1 | |
| SCHEMBL30299305 | 0.85 | ALDH1A1 (0.38) | L3MBTL3L3MBTL1HRH3NPY2RMBTD1 | |
| SCHEMBL30299345 | 0.84 | AXL (0.38) | L3MBTL3L3MBTL1HRH3NPY2RMBTD1 | |
| SCHEMBL30299390 | 0.84 | PDCD1 (0.38) | L3MBTL3L3MBTL1HRH3SOS1ALK | |
| SCHEMBL30299368 | 0.80 | GAA (0.38) | — | |
| SCHEMBL30299283 | 0.80 | L3MBTL3 (0.54) | L3MBTL3L3MBTL1MBTD1 | |
| SCHEMBL30299369 | 0.78 | AXL (0.37) | HRH3ALK | |
| SCHEMBL30090486 | 0.78 | KCNH2 (0.39) | L3MBTL1FGFR1RETROS1FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116075303-A | Method of selecting patients treated with a combination of an AXL inhibitor and an immune checkpoint modulator | 卑尔根生物股份公司 | 2023-05-05 | — | — | CN | disclosed |
| CN-115916344-A | AXL inhibitors for antiviral therapy | 卑尔根生物股份公司 | 2023-04-04 | — | — | CN | disclosed |