Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 12/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | OGA | O60502 | 1/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12758905 | 0.89 | TMEM97 (0.48) | LRRK2CYP2C19CYP2C9MAPK1MEN1 | |
| SCHEMBL14996508 | 0.84 | PRDM9 (0.42) | LRRK2CYP2C19CYP2C9MEN1KMT2A | |
| SCHEMBL20468944 | 0.82 | ALDH1A1 (0.49) | LRRK2CYP2C19CYP2C9MAPK1MEN1 | |
| SCHEMBL13168224 | 0.80 | OGA (0.46) | LRRK2CYP2C19CYP2C9MAPK1CYP2D6 | |
| SCHEMBL13131094 | 0.80 | PRDM9 (0.40) | LRRK2CYP2C19CYP2C9CYP3A4CYP2D6 | |
| SCHEMBL425041 | 0.77 | HRH4 (0.56) | MAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL21186191 | 0.76 | HRH4 (0.50) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13131256 | 0.75 | SLC6A2 (0.44) | CYP2C19CYP2C9MAPK1MEN1KMT2A | |
| SCHEMBL9455784 | 0.75 | HRH4 (0.58) | MAPK1MEN1KMT2ATSHRALDH1A1 | |
| Water SCHEMBL28114608 | 0.75 | HRH4 (0.54) | MAPK1MEN1KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115843295-A | NAMPT modulators | 赛特凯恩蒂克公司 | 2023-03-24 | — | — | CN | disclosed |