Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 4/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.40 |
| ▸ | PRDM9 | Q9NQV7 | 1/20 | 0.38 |
| ▸ | PRDM7 | Q9NQW5 | 1/20 | 0.38 |
| ▸ | WNT3A | P56704 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13168164 | 0.83 | OGA (0.52) | OGATMEM97LRRK2GAARAD52 | |
| SCHEMBL13168755 | 0.82 | AR (0.41) | OGATSHRCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL14996508 | 0.82 | PRDM9 (0.42) | OGATMEM97LRRK2PRDM9PRDM7 | |
| SCHEMBL12944876 | 0.81 | CYP2C9 (0.52) | TSHRCYP1A2CYP2D6CYP2C19CYP2C9 | |
| SCHEMBL30306686 | 0.80 | LRRK2 (0.47) | OGATMEM97LRRK2TSHRCYP1A2 | |
| SCHEMBL13131094 | 0.78 | PRDM9 (0.40) | OGATMEM97LRRK2PRDM9PRDM7 | |
| SCHEMBL21186191 | 0.75 | HRH4 (0.50) | PRDM9PRDM7GAALDHA | |
| SCHEMBL11955030 | 0.75 | CYP2C19 (0.53) | TSHRCYP1A2CYP2D6CYP2C19CYP2C9 | |
| SCHEMBL13168229 | 0.74 | PHGDH (0.41) | OGAGAARAD52TSHRCYP1A2 | |
| SCHEMBL11955830 | 0.74 | CYP3A4 (0.54) | TSHRCYP1A2CYP2D6CYP2C19CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100249095-A1 | Substituted Spiro-amide Compounds | GRUENENTHAL GMBH (DE) | 2010-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100249095-A1 | Substituted Spiro-amide Compounds | BDKRB1, BDKRB2, REN | OGA 3406/4885TMEM97 1662/4885LRRK2 322/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.