SCHEMBL3032849

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	Trifluoroacetic Acid SCHEMBL3033032	0.95	MAPK8 (0.37)	MAPK8ALDH1A1TDP1L3MBTL1LMNA
	SCHEMBL13982264	0.89	POLB (0.37)	PTGESP2RX7POLB
	SCHEMBL3806168	0.87	CYP3A4 (0.42)	PKMMAPK1PTGESSMN1; SMN2
	SCHEMBL13217563	0.86	PKM (0.40)	MAPK8ALDH1A1TDP1L3MBTL1LMNA
	SCHEMBL13982259	0.85	CYP3A4 (0.38)	PTGESP2RX7
	SCHEMBL13982109	0.85	CYP3A4 (0.33)	PTGESP2RX7ROCK2ROCK1
	SCHEMBL13982160	0.85	PTGES (0.36)	PTGES
	SCHEMBL13982434	0.85	PTGES (0.35)	ALDH1A1PTGESP2RX7KMT2A
	SCHEMBL13982372	0.85	PTGES (0.37)	ALDH1A1HTTPTGESP2RX7ROCK2
	SCHEMBL13981694	0.84	PTGES (0.33)	PTGESP2RX7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.