Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3602648 | 0.88 | SIGMAR1 (0.43) | POLBCYP2D6CYP2C9CYP2C19KMT2A | |
| SCHEMBL30801751 | 0.83 | KCNH2 (0.38) | POLBPKM | |
| SCHEMBL30337144 | 0.78 | SLC6A2 (0.44) | POLBCYP2D6CYP2C9CYP2C19KMT2A | |
| SCHEMBL8593861 | 0.78 | SMN1; SMN2 (0.49) | SMN1; SMN2 | |
| SCHEMBL30801878 | 0.78 | TAAR1 (0.39) | KMT2ATAAR1 | |
| SCHEMBL14085914 | 0.77 | ALDH1A1 (0.49) | POLBCYP2D6CYP2C9CYP2C19KMT2A | |
| SCHEMBL30801898 | 0.75 | HTR2C (0.37) | TAAR1 | |
| SCHEMBL23573934 | 0.73 | CTSS (0.43) | POLBCYP2D6CYP2C9CYP2C19KMT2A | |
| SCHEMBL23573935 | 0.73 | CTSS (0.43) | POLBCYP2D6CYP2C9CYP2C19KMT2A | |
| SCHEMBL29516262 | 0.69 | SIGMAR1 (0.47) | POLBCYP2D6CYP2C9CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3793997-B1 | FUSED BICYCLIC COMPOUNDS USEFUL AS UBIQUITIN-SPECIFIC PEPTIDASE 30 INHIBITORS | FORMA THERAPEUTICS INC (US) | 2024-03-13 | — | — | EP | claimed |