Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPR | P35270 | 4/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.32 |
| ▸ | KDM5A | P29375 | 1/20 | 0.32 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | PDE4A | P27815 | 2/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.30 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16199065 | 0.69 | HPGD (0.46) | SPRGSK3BPOLBMEN1HPGD | |
| SCHEMBL22583529 | 0.62 | KDM4E (0.32) | MEN1HPGDKMT2A | |
| SCHEMBL22582875 | 0.62 | NOS3 (0.46) | POLBMEN1KMT2A | |
| SCHEMBL13927834 | 0.62 | GABRG2 (0.37) | POLBKDM4CKDM5AKDM5BKMT2A | |
| SCHEMBL5070874 | 0.60 | SPR (0.61) | SPRPOLBHPGDNR3C1 | |
| SCHEMBL15882236 | 0.60 | P2RX7 (0.31) | — | |
| SCHEMBL22583203 | 0.59 | — | — | |
| SCHEMBL28915484 | 0.59 | HSD17B10 (0.38) | POLBMEN1KMT2A | |
| SCHEMBL6386783 | 0.59 | NNMT (0.36) | POLBMEN1KMT2A | |
| SCHEMBL2094148 | 0.59 | SCN2A (0.51) | POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130165439-A1 | CHEMICAL COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-06-27 | — | — | US | disclosed |
| US-20100210644-A1 | CHEMICAL COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-08-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130165439-A1 | CHEMICAL COMPOUNDS | MKI67, CCNT1, CCNA1 | SPR 4284/4885GSK3B 998/4885POLB 3534/4885 |
| US-20100210644-A1 | CHEMICAL COMPOUNDS | MKI67, CCNA1, CCNT1 | SPR 4323/4885GSK3B 1012/4885POLB 3599/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.