Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 5/20 | 0.40 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.36 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.34 |
| ▸ | TUBB | P07437 | 1/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.34 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.34 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.34 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.34 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.34 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.34 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.34 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.34 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.34 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.34 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22386326 | 0.82 | ROCK2 (0.39) | ROCK2SMN1; SMN2ALDH1A1LMNAHSD17B10 | |
| SCHEMBL22522218 | 0.79 | XDH (0.46) | ROCK2TET2TET1MAPTSMN1; SMN2 | |
| SCHEMBL30364487 | 0.78 | FAAH (0.44) | ROCK2TET2TET1MAPTSMN1; SMN2 | |
| SCHEMBL22468302 | 0.77 | TET2 (0.60) | ROCK2TET2TET1SMN1; SMN2ALDH1A1 | |
| SCHEMBL2113288 | 0.76 | SMN1; SMN2 (0.52) | TET2TET1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL22809686 | 0.74 | ROCK2 (0.36) | ROCK2MAPTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL24017805 | 0.73 | HCAR1 (0.42) | MAPTSMN1; SMN2MEN1NPC1ALDH1A1 | |
| SCHEMBL22522557 | 0.73 | ALDH1A1 (0.46) | TET2TET1SMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL22421219 | 0.71 | CYP2A6 (0.44) | MAPTALDH1A1GAAHSD17B10 | |
| SCHEMBL23367952 | 0.70 | CYP3A4 (0.40) | ROCK2TET2TET1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3702355-A1 | SUBSTITUTED PYRAZOLE COMPOUNDS CONTAINING PYRIMIDINE, THE PREPARATION AND APPLICATION THEREOF | Shenyang Sinochem Agrochemicals R&D Co., Ltd. (CN) | 2020-09-02 | — | — | EP | disclosed |