SCHEMBL29357687

SCHEMBL29357687

CCCC[C@H](NC(C)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C(N)N)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)NCC(N)=O

nearest known ligand 0.75

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ KISS1R Q969F8 1/20 0.62
▸ MC4R P32245 15/20 0.61
▸ MC1R Q01726 11/20 0.61
▸ MC5R P33032 1/20 0.57
▸ MC3R P41968 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14188828 0.91 MC4R (0.68) MC4RMC1RMC5RMC3R
SCHEMBL26006253 0.88 KISS1R (0.64) KISS1RMC4RMC1RMC5RMC3R
SCHEMBL29359331 0.88 KISS1R (0.64) KISS1RMC4RMC1RMC5RMC3R
SCHEMBL26006274 0.88 KISS1R (0.64) KISS1RMC4RMC1RMC5RMC3R
SCHEMBL13035278 0.88 MC4R (0.68) MC4RMC1RMC5RMC3R
SCHEMBL30494060 0.87 KISS1R (0.60) KISS1RMC4RMC1R
SCHEMBL29398150 0.86 KISS1R (0.65) KISS1RMC4R
SCHEMBL30366588 0.84 KISS1R (0.60) KISS1RMC4R
SCHEMBL29519296 0.84 KISS1R (0.60) KISS1RMC4R
SCHEMBL14215855 0.82 MC4R (0.59) MC4RMC1RMC5RMC3R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 219 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4021413-A1 LIPOSOMAL TROPONOID COMPOUND FORMULATIONS United States Government as Represented by The Department of Veterans Affairs (US) 2022-07-06 — — EP claimed
EP-4107166-B1 HETEROARYL COMPOUNDS FOR TREATMENT OF COMPLEMENT FACTOR D MEDIATED DISORDERS ACHILLION PHARMACEUTICALS INC (US) 2026-05-27 — — EP disclosed
US-12624002-B2 Dimers for use in synthesis of peptidomimetics THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-05-12 — — US disclosed
US-12622922-B2 Compositions and methods for metal containing formulations capable of modulating immune response THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2026-05-12 — — US disclosed
US-12600699-B2 Thiosemicarbazates and uses thereof THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-04-14 — — US disclosed
US-12595233-B2 Thiosemicarbazates and uses thereof THE FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-04-07 — — US disclosed
US-20260092056-A1 MELANOCORTIN-4 RECEPTOR AGONISTS LG CHEMICAL LTD (KR) 2026-04-02 — — US disclosed
US-12590305-B2 Complement component C5 iRNA compositions and methods of use thereof ALNYLAM PHARMACEUTICALS, INC. (US) 2026-03-31 — — US disclosed
US-20260077012-A1 COMPOSITIONS AND METHODS FOR DIAGNOSIS AND TREATMENT OF NEURODEGENERATIVE DISEASES EPITRACKER INC (US) 2026-03-19 — — US disclosed
US-20260070894-A1 COMPOUNDS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS FEINSTEIN INSTITUTES FOR MEDICAL RESEARCH (US) 2026-03-12 — — US disclosed
US-20220079897-A1 METHODS OF TREATMENT FIRST WAVE BIO, INC. 2022-03-17 — — US disclosed
EP-3966201-A1 THIOSEMICARBAZATES AND USES THEREOF The Feinstein Institutes for Medical Research (US) 2022-03-16 — — EP disclosed
EP-3966223-A1 PEPTIDOMIMETIC AGENTS, SYNTHESIS AND USES THEREOF The Feinstein Institutes for Medical Research (US) 2022-03-16 — — EP disclosed
US-20220072023-A1 COMPOSITIONS AND METHODS FOR METAL CONTAINING FORMULATIONS CAPABLE OF MODULATING IMMUNE RESPONSE NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2022-03-10 — — US disclosed
CN-114126619-A Compounds for the synthesis of peptidomimetics 范因斯坦医学研究院 2022-03-01 — — CN disclosed
US-11254740-B2 Methods of treatment using IL-23p19 monoclonal antibodies BRISTOL-MYERS SQUIBB COMPANY (US) 2022-02-22 — — US disclosed
EP-3953327-A1 MELANOCORTIN-4 RECEPTOR AGONISTS LG CHEM, LTD. (KR) 2022-02-16 — — EP disclosed
CN-114044800-A Aryl, heteroaryl and heterocyclic compounds for the treatment of medical disorders 艾其林医药公司 2022-02-15 — — CN disclosed
US-11248037-B2 Multivalent heteromultimer scaffold design and constructs ZYMEWORKS INC. (CA) 2022-02-15 — — US disclosed
EP-3941462-A1 PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS Achillion Pharmaceuticals, Inc. (US) 2022-01-26 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12624002-B2 Dimers for use in synthesis of peptidomimetics GLUL, ARGLU1, ASNS KISS1R 586/4885MC4R 616/4885MC1R 640/4885
US-20260077012-A1 COMPOSITIONS AND METHODS FOR DIAGNOSIS AND TREATMENT OF NEURODEGENERATIVE DISEASES CD4, COL2A1, MMP1 KISS1R 3095/4885MC4R 3669/4885MC1R 992/4885
US-20220072023-A1 COMPOSITIONS AND METHODS FOR METAL CONTAINING FORMULATIONS CAPABLE OF MODULATING IMMUNE RESPONSE MYD88, STING1, TLR3 KISS1R 4274/4885MC4R 3054/4885MC1R 1399/4885
US-12590305-B2 Complement component C5 iRNA compositions and methods of use thereof UPF1, C5, NSUN2 KISS1R 4818/4885MC4R 4775/4885MC1R 2566/4885
US-20260070894-A1 COMPOUNDS FOR USE IN SYNTHESIS OF PEPTIDOMIMETICS NPR1, NGLY1, DDAH1 KISS1R 297/4885MC4R 455/4885MC1R 601/4885
US-12595233-B2 Thiosemicarbazates and uses thereof TST, THRB, HSPB1 KISS1R 3677/4885MC4R 1730/4885MC1R 1434/4885
US-20220079897-A1 METHODS OF TREATMENT ACE2, ACE, SI KISS1R 286/4885MC4R 2077/4885MC1R 3454/4885
US-20260092056-A1 MELANOCORTIN-4 RECEPTOR AGONISTS MC5R, MC4R, MC3R KISS1R 46/4885MC4R 2/4885MC1R 5/4885
US-12622922-B2 Compositions and methods for metal containing formulations capable of modulating immune response STING1, CGAS, TLR3 KISS1R 1564/4885MC4R 2222/4885MC1R 476/4885
US-12600699-B2 Thiosemicarbazates and uses thereof MET, THRB, ABAT KISS1R 2445/4885MC4R 222/4885MC1R 338/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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