Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | ACVR1 | Q04771 | 4/20 | 0.32 |
| ▸ | MRGPRX2 | Q96LB1 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3030864 | 0.92 | PIM1 (0.36) | PIM1ACVR1 | |
| SCHEMBL3039262 | 0.87 | ALDH1A1 (0.37) | PIM1ACVR1MRGPRX2HRH3 | |
| SCHEMBL3035433 | 0.86 | HRH3 (0.42) | HRH3 | |
| SCHEMBL13177796 | 0.66 | ALK (0.44) | ACVR1 | |
| SCHEMBL5836183 | 0.65 | MAPT (0.59) | ACVR1HRH3 | |
| SCHEMBL3034338 | 0.64 | TSHR (0.37) | HRH3 | |
| SCHEMBL15823491 | 0.62 | TRPV6 (0.43) | — | |
| SCHEMBL5836939 | 0.61 | KDM4E (0.53) | HRH3 | |
| SCHEMBL8439285 | 0.61 | NCF1 (0.41) | PIM1 | |
| SCHEMBL18379027 | 0.61 | NCF1 (0.41) | PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111406-A2 | COMPOUNDS AND THERAPEUTIC USES THEREOF | MYRIAD PHARMACEUTICALS, INC. (US) | 2010-09-30 | — | — | WO | claimed |