Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | ACVR1 | Q04771 | 8/20 | 0.35 |
| ▸ | FGFR3 | P22607 | 6/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | VCP | P55072 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | INSR | P06213 | 2/20 | 0.32 |
| ▸ | IGF1R | P08069 | 2/20 | 0.32 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3039262 | 0.95 | ALDH1A1 (0.37) | PIM1ACVR1FGFR3KCNH2ALDH1A1 | |
| SCHEMBL3038009 | 0.92 | PIM1 (0.33) | PIM1ACVR1 | |
| SCHEMBL3035433 | 0.77 | HRH3 (0.42) | ALDH1A1 | |
| SCHEMBL3034338 | 0.69 | TSHR (0.37) | KCNH2ALDH1A1 | |
| SCHEMBL15823491 | 0.67 | TRPV6 (0.43) | ALDH1A1 | |
| SCHEMBL26418370 | 0.65 | DRD2 (0.71) | ALDH1A1 | |
| SCHEMBL19288664 | 0.64 | TSHR (0.61) | KCNH2VCPALDH1A1 | |
| SCHEMBL30378754 | 0.64 | TSHR (0.61) | KCNH2VCPALDH1A1 | |
| SCHEMBL3436969 | 0.64 | L3MBTL1 (0.46) | PIM1ACVR1VCPALDH1A1 | |
| SCHEMBL13849358 | 0.63 | FGFR3 (0.46) | ACVR1FGFR3KCNH2INSRIGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111406-A2 | COMPOUNDS AND THERAPEUTIC USES THEREOF | MYRIAD PHARMACEUTICALS, INC. (US) | 2010-09-30 | — | — | WO | claimed |