Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | MRGPRX2 | Q96LB1 | 1/20 | 0.31 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3030864 | 0.95 | PIM1 (0.36) | ALDH1A1PIM1FGFR3KCNH2ACVR1 | |
| SCHEMBL3038009 | 0.87 | PIM1 (0.33) | HRH3PIM1MRGPRX2ACVR1 | |
| SCHEMBL3035433 | 0.80 | HRH3 (0.42) | ALDH1A1HRH3TDP1 | |
| SCHEMBL3034338 | 0.71 | TSHR (0.37) | ALDH1A1KDM4EHRH3KCNH2 | |
| SCHEMBL15823491 | 0.67 | TRPV6 (0.43) | ALDH1A1L3MBTL1L3MBTL3KDM4ETDP1 | |
| SCHEMBL3033304 | 0.66 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1KDM4E | |
| SCHEMBL26042916 | 0.66 | L3MBTL3 (0.47) | ALDH1A1L3MBTL1L3MBTL3PIM1 | |
| SCHEMBL28503601 | 0.64 | ALDH1A1 (0.41) | ALDH1A1KDM4EPIM1FGFR3KCNH2 | |
| SCHEMBL3436969 | 0.64 | L3MBTL1 (0.46) | ALDH1A1L3MBTL1L3MBTL3KDM4EHRH3 | |
| SCHEMBL12772837 | 0.64 | L3MBTL3 (0.46) | ALDH1A1L3MBTL1L3MBTL3KDM4EHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111406-A2 | COMPOUNDS AND THERAPEUTIC USES THEREOF | MYRIAD PHARMACEUTICALS, INC. (US) | 2010-09-30 | — | — | WO | claimed |