Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | SCN1A | P35498 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3033279 | 0.89 | HRH3 (0.36) | CYP2D6DRD2ALDH1A1CYP1A2HTR2A | |
| SCHEMBL2946349 | 0.88 | CYP2C19 (0.36) | SMN1; SMN2ALDH1A1MAPK1KDM4E | |
| SCHEMBL3031209 | 0.83 | GAA (0.40) | CYP2D6SMN1; SMN2ALDH1A1 | |
| SCHEMBL3033304 | 0.80 | ALDH1A1 (0.45) | TSHRSMN1; SMN2ALDH1A1NPSR1KDM4E | |
| SCHEMBL3039262 | 0.71 | ALDH1A1 (0.37) | ALDH1A1KCNH2HRH3KDM4E | |
| SCHEMBL3030864 | 0.69 | PIM1 (0.36) | ALDH1A1KCNH2 | |
| SCHEMBL5069635 | 0.64 | LMNA (0.34) | SMN1; SMN2ALDH1A1CYP1A2MAPK1KDM4E | |
| SCHEMBL11856358 | 0.62 | KDM4E (0.70) | TSHRSMN1; SMN2ALDH1A1SIGMAR1KDM4E | |
| SCHEMBL1906001 | 0.61 | LMNA (0.36) | ALDH1A1NPSR1KDM4E | |
| SCHEMBL17024319 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111406-A2 | COMPOUNDS AND THERAPEUTIC USES THEREOF | MYRIAD PHARMACEUTICALS, INC. (US) | 2010-09-30 | — | — | WO | claimed |