Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE known ✓ | P12821 | 1/20 | 0.40 |
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.39 |
| ▸ | ADRA2A known ✓ | P08913 | 1/20 | 0.39 |
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 known ✓ | P31645 | 1/20 | 0.39 |
| ▸ | ADRA1A known ✓ | P35348 | 1/20 | 0.39 |
| ▸ | DRD3 known ✓ | P35462 | 1/20 | 0.39 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | EYA2 | O00167 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL1825839 | 1.00 | TDP1 (0.40) | TDP1EYA2APPACEBLM | |
| SCHEMBL1477656 | 0.98 | TDP1 (0.42) | TDP1EYA2APPACEBLM | |
| SCHEMBL93743 | 0.98 | TDP1 (0.42) | TDP1EYA2APPACEBLM | |
| SCHEMBL21848627 | 0.98 | TDP1 (0.42) | TDP1EYA2APPACEBLM | |
| SCHEMBL367170 | 0.98 | TDP1 (0.42) | TDP1EYA2APPACEBLM | |
| SCHEMBL641988 | 0.98 | TDP1 (0.42) | TDP1EYA2APPACEBLM | |
| SCHEMBL7705689 | 0.95 | TDP1 (0.40) | TDP1EYA2APPACEBLM | |
| SCHEMBL643078 | 0.93 | TDP1 (0.36) | TDP1EYA2APPACEBLM | |
| SCHEMBL19962832 | 0.91 | TDP1 (0.42) | TDP1EYA2APPACEBLM | |
| SCHEMBL19962167 | 0.91 | TDP1 (0.42) | TDP1EYA2APPACEBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 417 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12601975-B2 | Compositions for reducing resist consumption of extreme ultraviolet metallic type resist | TAIWAN SEMICONDUCTOR MANUFACTURING CO., LTD. (TW) | 2026-04-14 | — | — | US | claimed |
| US-12487527-B2 | Photoresist developer and method of developing photoresist | TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD. (TW) | 2025-12-02 | — | — | US | claimed |
| US-20250362598-A1 | PHOTORESIST DEVELOPER AND METHOD OF DEVELOPING PHOTORESIST | TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD. (TW) | 2025-11-27 | — | — | US | claimed |
| US-20250136488-A1 | Extended- and Multimodal-Release Compositions | Finoric LLC | 2025-05-01 | — | — | US | claimed |
| US-20240264526-A1 | PHOTORESIST DEVELOPER AND METHOD OF DEVELOPING PHOTORESIST | TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD. (TW) | 2024-08-08 | — | — | US | claimed |
| US-11971657-B2 | Photoresist developer and method of developing photoresist | TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD. (TW) | 2024-04-30 | — | — | US | claimed |
| CN-116692927-A | Preparation method of high-purity silver nitrate | 昆明冶金研究院有限公司 | 2023-09-05 | — | — | CN | claimed |
| US-20230033363-A1 | AQUEOUS SOLUTIONS CONTAINING AMINO CARBOXYLIC ACID CHELATORS | ASCEND PERFORMANCE MATERIALS OPERATIONS LLC (US) | 2023-02-02 | — | — | US | claimed |
| CN-115532793-A | Process method for reducing soluble manganese and ammonia nitrogen in electrolytic manganese slag | 梁毅 | 2022-12-30 | — | — | CN | claimed |
| US-20220404705-A1 | COMPOSITIONS FOR REDUCING RESIST CONSUMPTION OF EXTREME ULTRAVIOLET METALLIC TYPE RESIST | TAIWAN SEMICONDUCTOR MANUFACTURING COMPANY, LTD. (TW) | 2022-12-22 | — | — | US | claimed |
| EP-1786879-A2 | METHOD OF REMOVING AN INVERT EMULSION FILTER CAKE AFTER THE DRILLING PROCESS USING A SINGLE PHASE MICROEMULSION | Baker Hughes Incorporated (US) | 2007-05-23 | — | — | EP | claimed |
| EP-1760737-A1 | ELECTROLYTE FOR DRIVING ELECTROLYTIC CAPACITOR AND ELECTROLYTIC CAPACITOR | Rubycon Corporation (JP) | 2007-03-07 | — | — | EP | claimed |
| US-20070027253-A1 | Method of removing an invert emulsion filter cake after the drilling process using a single phase microemulsion | BAKER HUGHES INCORPORATED | 2007-02-01 | — | — | US | claimed |
| US-7134496-B2 | Method of removing an invert emulsion filter cake after the drilling process using a single phase microemulsion | BAKER HUGHES INCORPORATED (US) | 2006-11-14 | — | — | US | claimed |
| US-20060073986-A1 | Method of removing an invert emulsion filter cake after the drilling process using a single phase microemulsion | BAKER HUGHES INCORPORATED (US) | 2006-04-06 | — | — | US | claimed |
| WO-2006029019-A2 | METHOD OF REMOVING AN INVERT EMULSION FILTER CAKE AFTER THE DRILLING PROCESS USING A SINGLE PHASE MICROEMULSION | BAKER HUGHES INCORPORATED (US) | 2006-03-16 | — | — | WO | claimed |
| EP-1006536-B1 | Electrolytic solution for electrolytic capacitor and electrolytic capacitor using the same | RUBYCON CORP (JP) | 2006-03-15 | — | — | EP | claimed |
| US-20050143286-A1 | such as lactoferrin, conalbumin; combinations with antibiotics, microbiocides for e.g. disinfecting, preserving food, treating infections; also chelating agents such as ,19,30-trioxa-1,4,10,13,16,22,27,33-octaazabicyclo(11,11,11)pentatriacontane hexahydrobromide | THE UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2005-06-30 | — | — | US | claimed |
| US-6288889-B1 | SOLVENT OF AN ORGANIC SOLVENT AND WATER, AN ELECTROLYTE OF CARBOXYLIC ACIDS, INORGANIC ACIDS, AND/OR THEIR SALTS, AND A CHELATE COMPOUND; LOW TEMPERATURE STABILITY AND IMPEDANCE | RUBYCON CORPORATION (JP) | 2001-09-11 | — | — | US | claimed |
| EP-1006536-A2 | Electrolytic solution for electrolytic capacitor and electrolytic capacitor using the same | Rubycon Corporation (JP) | 2000-06-07 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12601975-B2 | Compositions for reducing resist consumption of extreme ultraviolet metallic type resist | ADH1C, GRIN2C, MCCC2 | ACE 4215/4885CHRM2 263/4885ADRA2A 851/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.