SCHEMBL30387201

SCHEMBL30387201

Cc1cc2c(cc1F)OCC(=O)CO2

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
PDE3B Q13370 2/20 0.33
PDE3A Q14432 2/20 0.33
TSHR P16473 2/20 0.33
KDM4E B2RXH2 2/20 0.33
ALDH1A1 P00352 2/20 0.33
GAA P10253 1/20 0.33
HPGD P15428 1/20 0.33
HSD17B10 Q99714 1/20 0.33
MMP12 P39900 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.32
DAO P14920 1/20 0.32
PTGS1 P23219 1/20 0.31
IMPDH2 P12268 1/20 0.31
IMPDH1 P20839 1/20 0.31
PGR P06401 1/20 0.31
NR3C2 P08235 1/20 0.31
PKM P14618 1/20 0.31
KMO O15229 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6570348 0.85 IMPDH2 (0.39) NPC1RAB9APDE3BPDE3ATSHR
SCHEMBL12116768 0.79 ALDH1A1 (0.40) NPC1RAB9ATSHRKDM4EALDH1A1
SCHEMBL8259845 0.79 NPC1 (0.46) NPC1RAB9AALDH1A1HPGD
SCHEMBL19627161 0.77 HSD17B10 (0.39) NPC1RAB9APDE3BPDE3AKDM4E
SCHEMBL12060295 0.73 TP53 (0.57) MMP12PGRNR3C2PKMTP53
SCHEMBL30043257 0.69 MMP12 (0.53) NPC1RAB9ATSHRKDM4EALDH1A1
SCHEMBL235690 0.69 MMP12 (0.53) NPC1RAB9ATSHRKDM4EALDH1A1
SCHEMBL13950590 0.67 PKM (0.33) PKM
SCHEMBL6569375 0.67 TSHR (0.36) PDE3BPDE3ATSHRALDH1A1MMP12
SCHEMBL31191969 0.66 MAOB (0.38) NPC1RAB9AKDM4EALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116056572-A Oil-based drift control composition 蓝宝迪有限公司 2023-05-02 CN disclosed