SCHEMBL304015

SCHEMBL304015

Brc1ccc2c(c1)OCCN2

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.49
ALDH1A1 P00352 2/20 0.49
GAA P10253 2/20 0.49
HSD17B10 Q99714 2/20 0.49
LMNA P02545 1/20 0.48
HTT P42858 1/20 0.48
BLM P54132 1/20 0.48
HDAC11 Q96DB2 1/20 0.40
PDE3B Q13370 2/20 0.39
PDE3A Q14432 2/20 0.39
AHR P35869 3/20 0.39
KDM4E B2RXH2 1/20 0.39
GLA P06280 1/20 0.39
HPGD P15428 1/20 0.39
CASP1 P29466 1/20 0.39
CASP7 P55210 1/20 0.39
ATM Q13315 1/20 0.39
TRPV1 Q8NER1 1/20 0.38
EGFR P00533 1/20 0.38
FABP6 P51161 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30023822 1.00 MAPT (0.49) MAPTALDH1A1GAAHSD17B10LMNA
SCHEMBL15479695 0.90 LMNA (0.61) MAPTALDH1A1GAAHSD17B10LMNA
SCHEMBL31133734 0.87 MAPT (0.44) MAPTALDH1A1GAAHSD17B10LMNA
SCHEMBL304283 0.85 MAPT (0.62) MAPTALDH1A1GAAHSD17B10LMNA
SCHEMBL30895878 0.85 MAPT (0.62) MAPTALDH1A1GAAHSD17B10LMNA
Hydrochloric Acid SCHEMBL1820257 0.83 MAPT (0.61) MAPTALDH1A1GAAHSD17B10LMNA
SCHEMBL15479709 0.83 LMNA (0.53) MAPTALDH1A1GAAHSD17B10LMNA
SCHEMBL17423918 0.80 BLM (0.42) MAPTLMNAHTTBLMAHR
SCHEMBL24820913 0.77 ALDH1A1 (0.49) MAPTALDH1A1GAAHSD17B10HDAC11
SCHEMBL2746377 0.77 ALDH1A1 (0.49) MAPTALDH1A1GAAHSD17B10HDAC11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4720057-A2 COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF Oncopia Therapeutics, Inc. D/B/A SK Life Science Labs (US) 2026-04-08 EP disclosed
US-20260078117-A1 COMPOUNDS AND METHODS OF USE TANGO THERAPEUTICS INC (US) 2026-03-19 US disclosed
US-20260078134-A1 Macrocyclic Compounds as RAS Inhibitors BEONE MEDICINES I GMBH (CH) 2026-03-19 US disclosed
US-12570648-B2 6,7-dihydro-5H-pyrido[2,3-c]pyridazine derivatives and related compounds as Bcl-xL protein inhibitors and pro-apoptotic agents for treating cancer LES LABORATOIRES SERVIER (FR) 2026-03-10 US disclosed
US-20260015321-A1 CHEMICAL COMPOUNDS AND USES THEREOF GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.4) LIMITED (GB) 2026-01-15 US disclosed
US-20250382285-A1 BICYCLIC-SUBSTITUTED GLUTARIMIDE CEREBLON BINDERS C4 THERAPEUTICS, INC. (US) 2025-12-18 US disclosed
US-20250368631-A1 BICYCLIC-SUBSTITUTED GLUTARIMIDE CEREBLON BINDERS C4 THERAPEUTICS, INC. (US) 2025-12-04 US disclosed
US-12486251-B2 CBP/EP300 inhibitor and use thereof PHARMABLOCK SCIENCES (NANJING) , INC. (CN) 2025-12-02 US disclosed
US-20250333407-A1 Compounds and Their Use for Treatment of Hemoglobinopathies BRISTOL-MYERS SQUIBB COMPANY (US) 2025-10-30 US disclosed
WO-2025201477-A1 SPIROCYCLIC GSDME INHIBITORS PYROTECH (BEIJING) BIOTECHNOLOGY CO.,LTD. (CN) 2025-10-02 WO disclosed
EP-2084155-A1 THIAZOLE DERIVATIVES AS KINASE INHIBITORS UCB Pharma S.A. (BE) 2009-08-05 EP disclosed
EP-2035436-A1 FUSED THIAZOLE DERIVATIVES AS KINASE INHIBITORS UCB Pharma S.A. (BE) 2009-03-18 EP disclosed
WO-2008047109-A1 THIAZOLE DERIVATIVES AS KINASE INHIBITORS UCB PHARMA S.A. (BE) 2008-04-24 WO disclosed
WO-2008001076-A1 FUSED THIAZOLE DERIVATIVES AS KINASE INHIBITORS UCB PHARMA S.A. (BE) 2008-01-03 WO disclosed
US-7312209-B2 Acridone inhibitors of IMPDH enzyme BRISTOL-MYERS SQUIBB COMPANY (US) 2007-12-25 US disclosed
US-7312209-B2 Acridone inhibitors of IMPDH enzyme BRISTOL-MYERS SQUIBB COMPANY (US) 2007-12-25 US disclosed
EP-1056728-B1 DIHYDRO-BENZO(1,4)OXAZINES AND TETRAHYDROQUINOXALINES AVENTIS PHARMA LTD (GB) 2007-11-21 EP disclosed
US-6632814-B1 Dihydro-benzo(1,4)oxazines AVENTIS PHARMA LTD. (GB) 2003-10-14 US disclosed
EP-1056728-A1 DIHYDRO-BENZO(1,4)OXAZINES AND TETRAHYDROQUINOXALINES Aventis Pharma Limited (GB) 2000-12-06 EP disclosed
WO-2000039103-A1 DIHYDRO-BENZO(1,4)OXAZINES AND TETRAHYDROQUINOXALINES AVENTIS PHARMA LIMITED (GB) 2000-07-06 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250368631-A1 BICYCLIC-SUBSTITUTED GLUTARIMIDE CEREBLON BINDERS CRBN, STUB1, CUL1 MAPT 1299/4885ALDH1A1 2876/4885GAA 986/4885
US-20260078134-A1 Macrocyclic Compounds as RAS Inhibitors NRAS, KRAS, HRAS MAPT 4125/4885ALDH1A1 2557/4885GAA 3111/4885
US-20260015321-A1 CHEMICAL COMPOUNDS AND USES THEREOF WRN, MSH2, MSH6 MAPT 4063/4885ALDH1A1 1151/4885GAA 1967/4885
US-12570648-B2 6,7-dihydro-5H-pyrido[2,3-c]pyridazine derivatives and related compounds as Bcl-xL protein inhibitors and pro-apoptotic agents for treating cancer BCOR, BCL2A1, BAK1 MAPT 4819/4885ALDH1A1 2522/4885GAA 4749/4885
US-20250382285-A1 BICYCLIC-SUBSTITUTED GLUTARIMIDE CEREBLON BINDERS CRBN, STUB1, CUL1 MAPT 1299/4885ALDH1A1 2876/4885GAA 986/4885
US-12486251-B2 CBP/EP300 inhibitor and use thereof EP300, CREBBP, BPTF MAPT 2797/4885ALDH1A1 2314/4885GAA 4668/4885
US-20250333407-A1 Compounds and Their Use for Treatment of Hemoglobinopathies HBG1, HBG2, HBB MAPT 4543/4885ALDH1A1 424/4885GAA 107/4885
US-20260078117-A1 COMPOUNDS AND METHODS OF USE NR3C2, ADRA1A, CNR1 MAPT 4259/4885ALDH1A1 100/4885GAA 2519/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.