SCHEMBL30403254

SCHEMBL30403254

COn1c(C(=O)O)cc2ccc(C(F)(F)F)cc21

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR2 P41597 2/20 0.50
PLA2G10 O15496 2/20 0.43
PLA2G2A P14555 1/20 0.43
PLA2G5 P39877 1/20 0.43
CCR9 P51686 6/20 0.42
KDM4E B2RXH2 3/20 0.40
ALDH1A1 P00352 3/20 0.40
HPGD P15428 3/20 0.40
HSD17B10 Q99714 3/20 0.40
USP2 O75604 1/20 0.40
CYP2C19 P33261 1/20 0.40
MCL1 Q07820 1/20 0.39
CFTR P13569 1/20 0.38
PIM1 P11309 1/20 0.38
PIM2 Q9P1W9 1/20 0.38
MAT2A P31153 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
DAO P14920 1/20 0.36
RORC P51449 1/20 0.36
SORT1 Q99523 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2140750 0.81 MCL1 (0.57) CCR2PLA2G10PLA2G2APLA2G5CCR9
SCHEMBL30667339 0.81 MCL1 (0.57) CCR2PLA2G10PLA2G2APLA2G5CCR9
SCHEMBL4445494 0.75 MCL1 (0.62) CCR2PLA2G10KDM4EALDH1A1HPGD
SCHEMBL10253563 0.72 KDM4E (0.65) CCR2KDM4EALDH1A1HPGDHSD17B10
SCHEMBL30995189 0.71 CCR2 (0.47) CCR2PLA2G10PLA2G2APLA2G5KDM4E
SCHEMBL15361987 0.69 CCR2 (0.71) CCR2CCR9
SCHEMBL7574 0.69 LDHA (0.71) CCR2DAORORC
SCHEMBL15473611 0.69 ALDH1A1 (0.47) CCR2KDM4EALDH1A1HPGDHSD17B10
SCHEMBL2139773 0.69 ALOX5 (0.46) CCR2KDM4EALDH1A1SMN1; SMN2
SCHEMBL30395344 0.68 NTRK1 (0.48) CCR9KDM4EALDH1A1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116096714-A Antiviral compounds for the treatment of coronavirus, picornavirus and norovirus infections 安力高医药股份有限公司 2023-05-09 CN disclosed