Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.38 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.36 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.36 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.36 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.36 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.36 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30406544 | 0.94 | CYP19A1 (0.40) | CYP19A1SMN1; SMN2LMNACACNA1BPTK2 | |
| SCHEMBL29973640 | 0.87 | CYP19A1 (0.40) | QPCTCYP19A1SMN1; SMN2LMNACACNA1B | |
| SCHEMBL23608966 | 0.87 | CYP19A1 (0.40) | QPCTCYP19A1SMN1; SMN2LMNACACNA1B | |
| SCHEMBL6965842 | 0.79 | CYP19A1 (0.54) | QPCTCYP19A1SMN1; SMN2LMNAMAPK1 | |
| SCHEMBL23608953 | 0.72 | CYP19A1 (0.38) | CYP19A1SMN1; SMN2LMNACACNA1BPTK2 | |
| SCHEMBL23608948 | 0.71 | GPR55 (0.47) | CYP19A1SMN1; SMN2LMNACACNA1BMAPK1 | |
| SCHEMBL30406696 | 0.69 | NTRK1 (0.35) | QPCTCYP19A1SMN1; SMN2LMNACACNA1B | |
| SCHEMBL23608983 | 0.69 | CYP19A1 (0.43) | CYP19A1SMN1; SMN2LMNAKDRKDM4E | |
| SCHEMBL23609248 | 0.68 | TLR8 (0.45) | CYP19A1SMN1; SMN2LMNAMAPK1CSNK2A2 | |
| SCHEMBL23608949 | 0.68 | CYP19A1 (0.44) | CYP19A1LMNAMAPK1ACHEKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230117592-A1 | LIPOXYGENASE INHIBITORS | SRI INTERNATIONAL (US) | 2023-04-20 | — | — | US | disclosed |
| WO-2021133689-A2 | LIPOXYGENASE INHIBITORS | SRI INTERNATIONAL (US) | 2021-07-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230117592-A1 | LIPOXYGENASE INHIBITORS | ALOX15B, ALOX12, ALOX5 | QPCT 1402/4885CYP19A1 153/4885SMN1; SMN2 243/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.