SCHEMBL304081

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4401018	0.88	NPC1 (0.56)	RAB9ANPC1KMT2AMAPTALDH1A1
	SCHEMBL476841	0.85	NR3C1 (0.47)	RAB9ANPC1KMT2AMAPTALDH1A1
	SCHEMBL1776385	0.84	MAPT (0.46)	RAB9ANPC1KMT2AMAPTALDH1A1
	SCHEMBL3972212	0.83	XDH (0.51)	RAB9ANPC1KMT2AMAPTALDH1A1
	SCHEMBL303854	0.81	RAB9A (0.44)	RAB9ANPC1KMT2AMAPTALDH1A1
	SCHEMBL4008059	0.78	TDP1 (0.56)	RAB9AKMT2AMAPTALDH1A1KDM4E
	SCHEMBL9609077	0.78	NR3C1 (0.46)	RAB9ANPC1KMT2AKDM4EHSD17B10
	SCHEMBL1775488	0.78	NR3C1 (0.48)	RAB9AKMT2AMAPTALDH1A1CYP1A2
	SCHEMBL303719	0.78	TDP1 (0.45)	RAB9ANPC1KMT2AMAPTALDH1A1
	SCHEMBL476793	0.77	CYP1A2 (0.51)	RAB9ANPC1KMT2AMAPTAPP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.