Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 7/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.40 |
| ▸ | CTSC | P53634 | 1/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30411625 | 0.81 | MME (0.56) | CTSC | |
| SCHEMBL30759335 | 0.77 | OPRM1 (0.49) | OPRD1OPRM1 | |
| Trifluoroacetic Acid SCHEMBL30164220 | 0.72 | PTPN1 (0.54) | CTSCPTPN1 | |
| Trifluoroacetic Acid SCHEMBL29484056 | 0.71 | MME (0.56) | — | |
| SCHEMBL30411524 | 0.71 | CTSS (0.42) | OPRK1OPRD1PTPN1 | |
| SCHEMBL29484064 | 0.70 | CTSL (0.50) | OPRK1OPRD1CTSCOPRM1 | |
| Trifluoroacetic Acid SCHEMBL11579813 | 0.69 | OPRK1 (0.62) | OPRK1CTSC | |
| SCHEMBL30862466 | 0.69 | MME (0.63) | CTSC | |
| SCHEMBL8082487 | 0.69 | MME (0.63) | CTSC | |
| SCHEMBL32690360 | 0.69 | HDAC3 (0.63) | OPRK1OPRD1CTSCOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023069332-A1 | CELL PERMEABLE MACROCYCLIC PEPTIDES USEFUL FOR EIF4E CAP-BINDING SITE INHIBITION | MERCK SHARP & DOHME LLC (US) | 2023-04-27 | — | — | WO | disclosed |