Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.53 |
| ▸ | HTR1A | P08908 | 2/20 | 0.52 |
| ▸ | DRD4 | P21917 | 1/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.50 |
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | HTR2C | P28335 | 2/20 | 0.47 |
| ▸ | HTR2B | P41595 | 2/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | GRM5 | P41594 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3055557 | 0.93 | HTR1A (0.50) | CHRNA7HTR1ADRD4DRD3GPR84 | |
| SCHEMBL3064135 | 0.89 | REV1 (0.56) | CHRNA7HTR1AGPR84LMNASMN1; SMN2 | |
| SCHEMBL3057161 | 0.87 | MAPK1 (0.55) | CHRNA7HTR1AGPR84LMNASMN1; SMN2 | |
| SCHEMBL3051832 | 0.86 | CHRNA7 (0.53) | CHRNA7HTR1AGPR84LMNASMN1; SMN2 | |
| SCHEMBL3051083 | 0.86 | HTR2A (0.54) | CHRNA7HTR1AGPR84LMNASMN1; SMN2 | |
| SCHEMBL31134765 | 0.86 | GRM5 (0.60) | DRD4GPR84HTR2BGRM5MEN1 | |
| SCHEMBL3061473 | 0.84 | ACHE (0.50) | HTR1ADRD4DRD3SMN1; SMN2GRM5 | |
| SCHEMBL3051019 | 0.81 | ROCK2 (0.53) | CHRNA7GPR84MEN1KMT2A | |
| SCHEMBL3186155 | 0.81 | GRM5 (0.45) | HTR1ADRD4DRD3GRM5ALDH1A1 | |
| SCHEMBL9620526 | 0.80 | MAOA (0.57) | CHRNA7HTR1AGPR84HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8394825-B2 | Compound | STERIX LIMITED (GB) | 2013-03-12 | — | — | US | disclosed |
| US-20100222299-A1 | COMPOUND | STERIX LIMITED (GB) | 2010-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100222299-A1 | COMPOUND | MKI67, VHL, MYC | CHRNA7 4760/4885HTR1A 1761/4885DRD4 1675/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.