Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 2/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.39 |
| ▸ | ITGAV | P06756 | 2/20 | 0.39 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.39 |
| ▸ | MDM4 | O15151 | 1/20 | 0.39 |
| ▸ | ENPEP | Q07075 | 5/20 | 0.38 |
| ▸ | TERT | O14746 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | CTSD | P07339 | 2/20 | 0.37 |
| ▸ | GNPAT | O15228 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31021037 | 0.88 | OPRM1 (0.41) | TERTOPRD1CTSDCTSB | |
| SCHEMBL29496724 | 0.86 | CA2 (0.46) | ENPEPTERTPTGS1GSTK1 | |
| SCHEMBL30683407 | 0.86 | ENPEP (0.45) | ENPEPCTSDGNPAT | |
| SCHEMBL29349612 | 0.85 | ALDH1A1 (0.42) | TERTOPRD1 | |
| SCHEMBL7308309 | 0.84 | ERAP2 (0.40) | ENPEPTERTOPRD1KEAP1CTSD | |
| SCHEMBL31410670 | 0.84 | OPRD1 (0.40) | OPRD1KEAP1CTSD | |
| SCHEMBL6891224 | 0.84 | OPRM1 (0.38) | ITGB3ITGB1ITGAVITGA5MDM2 | |
| SCHEMBL6891220 | 0.84 | OPRM1 (0.38) | ITGB3ITGB1ITGAVITGA5MDM2 | |
| SCHEMBL31410681 | 0.83 | BACE1 (0.44) | OPRD1CTSD | |
| SCHEMBL30720815 | 0.82 | BACE1 (0.46) | ENPEPOPRD1CTSDPTGS1GSTK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119462820-A | Carboline hexahydropyrazine-1, 4-diketone-3-acetyl-Gly-Gly as well as preparation and application thereof | 首都医科大学 | 2025-02-18 | — | — | CN | disclosed |
| CN-119390755-A | Carboline hexahydropyrazine-1, 4-diketone-3-acetyl-Val-Val, preparation and application thereof | 首都医科大学 | 2025-02-07 | — | — | CN | disclosed |
| US-11667694-B2 | Therapeutic uses of fibrinogen gamma prime variants | FIBRIANT B.V. (NL) | 2023-06-06 | — | — | US | disclosed |