Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 3/20 | 0.34 |
| ▸ | HTR2C | P28335 | 3/20 | 0.34 |
| ▸ | HTR2B | P41595 | 2/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30452454 | 0.90 | MAP3K14 (0.36) | MAP3K14KDM1AHTR2AHTR2CHTR2B | |
| SCHEMBL28336703 | 0.71 | AKR1A1 (0.39) | IDO1ESR2AKR1B1ALDH1A1 | |
| SCHEMBL28336692 | 0.70 | KMT2A (0.36) | IDO1KMT2A | |
| SCHEMBL28334555 | 0.69 | PPOX (0.39) | IDO1AKR1B1ALDH1A1 | |
| SCHEMBL28336730 | 0.68 | KMT2A (0.33) | MAP3K14HTR2AHTR2CHTR2BIDO1 | |
| SCHEMBL7473975 | 0.67 | IDO1 (0.48) | IDO1AKR1B1MEN1KMT2A | |
| SCHEMBL1921816 | 0.66 | PDK2 (0.42) | ESR2AKR1B1MEN1KMT2A | |
| SCHEMBL22515431 | 0.65 | MEN1 (0.34) | HTR2AHTR2CHTR2BESR2MEN1 | |
| SCHEMBL8696406 | 0.64 | IDO1 (0.51) | HTR2AIDO1AKR1B1MEN1KMT2A | |
| SCHEMBL28165119 | 0.64 | SIGMAR1 (0.40) | MAP3K14KDM1AHTR2CHTR2BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110563631-B | IDO inhibiting compound and application thereof | 爱斯特（成都）生物制药股份有限公司 | 2023-05-23 | — | — | CN | disclosed |