Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 2/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 2/20 | 0.35 |
| ▸ | PNMT | P11086 | 4/20 | 0.34 |
| ▸ | HTR2A | P28223 | 3/20 | 0.33 |
| ▸ | HTR2C | P28335 | 3/20 | 0.33 |
| ▸ | HTR2B | P41595 | 3/20 | 0.33 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30452208 | 0.90 | MAP3K14 (0.37) | MAP3K14ESR2KDM1AHTR2AHTR2C | |
| SCHEMBL28165119 | 0.74 | SIGMAR1 (0.40) | MAP3K14KDM1APNMTHTR2CHTR2B | |
| SCHEMBL28334555 | 0.70 | PPOX (0.39) | AKR1B1ALDH1A1 | |
| SCHEMBL28336730 | 0.69 | KMT2A (0.33) | MAP3K14ESR2HTR2AHTR2CHTR2B | |
| SCHEMBL28336703 | 0.68 | AKR1A1 (0.39) | ESR2AKR1B1ALDH1A1 | |
| SCHEMBL28336692 | 0.67 | KMT2A (0.36) | — | |
| SCHEMBL22515431 | 0.67 | MEN1 (0.34) | ESR2PNMTHTR2AHTR2CHTR2B | |
| SCHEMBL7473975 | 0.63 | IDO1 (0.48) | AKR1B1 | |
| SCHEMBL28318484 | 0.63 | CYP3A4 (0.39) | MAP3K14ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL1921816 | 0.62 | PDK2 (0.42) | ESR2AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110563631-B | IDO inhibiting compound and application thereof | 爱斯特（成都）生物制药股份有限公司 | 2023-05-23 | — | — | CN | disclosed |