Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 2/20 | 0.36 |
| ▸ | F9 | P00740 | 2/20 | 0.36 |
| ▸ | F10 | P00742 | 2/20 | 0.36 |
| ▸ | F12 | P00748 | 2/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.36 |
| ▸ | F7 | P08709 | 2/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.35 |
| ▸ | VEGFA | P15692 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22391591 | 0.77 | VEGFA (0.44) | MEN1MAPTHTTKMT2ANPSR1 | |
| SCHEMBL30502301 | 0.73 | HTR2C (0.44) | LMNATSHRPARP1 | |
| SCHEMBL30454719 | 0.73 | HTR1A (0.40) | HTTCYP3A4SLC6A2SLC6A4 | |
| SCHEMBL22392142 | 0.73 | HTR1A (0.40) | HTTCYP3A4SLC6A2SLC6A4 | |
| SCHEMBL31326208 | 0.73 | ALDH1A1 (0.40) | ALDH1A1LMNATSHRMEN1MAPT | |
| SCHEMBL31306949 | 0.72 | LMNA (0.41) | ALDH1A1LMNATSHRMEN1MAPT | |
| SCHEMBL873237 | 0.72 | RAD52 (0.41) | ALDH1A1LMNATSHRPARP1 | |
| SCHEMBL28052467 | 0.70 | TACR1 (0.40) | LMNATSHRPARP1 | |
| SCHEMBL5333905 | 0.70 | HTR2C (0.47) | PARP1 | |
| SCHEMBL1673503 | 0.70 | MEN1 (0.43) | ALDH1A1LMNATSHRMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113227068-B | GLP-1R agonists and uses thereof | 上海齐鲁锐格医药研发有限公司 | 2023-06-13 | — | — | CN | disclosed |