Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 2/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | RXRA | P19793 | 2/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25355182 | 1.00 | PDE4A (0.39) | PDE4APDE4BPDE4CPDE4DGAA | |
| SCHEMBL30454375 | 0.95 | GAA (0.38) | PDE4APDE4BPDE4CPDE4DGAA | |
| SCHEMBL25355935 | 0.95 | GAA (0.38) | PDE4APDE4BPDE4CPDE4DGAA | |
| SCHEMBL25355273 | 0.83 | ACHE (0.50) | ALDH1A1L3MBTL1KMT2ALMNAPOLB | |
| SCHEMBL30454767 | 0.83 | ACHE (0.50) | ALDH1A1L3MBTL1KMT2ALMNAPOLB | |
| SCHEMBL17050816 | 0.81 | L3MBTL1 (0.42) | ALDH1A1L3MBTL1KMT2ALMNAPOLB | |
| SCHEMBL25353410 | 0.79 | TRPA1 (0.37) | GAAALDH1A1L3MBTL1KMT2ALMNA | |
| SCHEMBL25355051 | 0.77 | ALOX15 (0.39) | GAAALDH1A1KMT2APOLBMAPT | |
| SCHEMBL738390 | 0.74 | DAO (0.39) | ALDH1A1RXRAGRIN1GRIN2BTHRB | |
| SCHEMBL29482231 | 0.74 | DAO (0.39) | ALDH1A1RXRAGRIN1GRIN2BTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122778-A1 | PYRIDAZINONE DERIVATIVES USEFUL AS T CELL ACTIVATORS | GOSSAMER BIO SERVICES, INC. (US) | 2023-06-29 | — | — | WO | disclosed |