Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 12/20 | 0.44 |
| ▸ | MAPT | P10636 | 11/20 | 0.44 |
| ▸ | HPGD | P15428 | 7/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25355273 | 1.00 | ACHE (0.50) | ACHEL3MBTL1MAPTHPGDNPC1 | |
| SCHEMBL17050816 | 0.86 | L3MBTL1 (0.42) | L3MBTL1MAPTHPGDNPC1RAB9A | |
| SCHEMBL25353410 | 0.83 | TRPA1 (0.37) | L3MBTL1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30455590 | 0.83 | PDE4A (0.39) | L3MBTL1MAPTHPGDNPC1RAB9A | |
| SCHEMBL25355182 | 0.83 | PDE4A (0.39) | L3MBTL1MAPTHPGDNPC1RAB9A | |
| SCHEMBL25355051 | 0.82 | ALOX15 (0.39) | MAPTHPGDNPC1RAB9ATDP1 | |
| SCHEMBL30454375 | 0.80 | GAA (0.38) | L3MBTL1MAPTHPGDNPC1RAB9A | |
| SCHEMBL25355935 | 0.80 | GAA (0.38) | L3MBTL1MAPTHPGDNPC1RAB9A | |
| SCHEMBL31498372 | 0.78 | HSPB1 (0.43) | L3MBTL1MAPTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL25354369 | 0.77 | SLC6A4 (0.42) | ALDH1A1POLBLMNAKDM4ESLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023122778-A1 | PYRIDAZINONE DERIVATIVES USEFUL AS T CELL ACTIVATORS | GOSSAMER BIO SERVICES, INC. (US) | 2023-06-29 | — | — | WO | disclosed |