Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | MMP9 | P14780 | 2/20 | 0.41 |
| ▸ | MMP12 | P39900 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.37 |
| ▸ | MMP14 | P50281 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5287421 | 0.77 | MMP2 (0.49) | LMNASMN1; SMN2L3MBTL1CYP2C9HPGD | |
| SCHEMBL11495787 | 0.74 | ALDH1A1 (0.46) | LMNASMN1; SMN2L3MBTL1TDP1SIRT5 | |
| SCHEMBL3041845 | 0.72 | HPGD (0.53) | LMNASMN1; SMN2L3MBTL1HPGDALDH1A1 | |
| SCHEMBL9472324 | 0.71 | APOBEC3G (0.61) | LMNASMN1; SMN2CYP2C9HPGDCYP2C19 | |
| SCHEMBL3765157 | 0.70 | HPGD (0.78) | LMNASMN1; SMN2L3MBTL1TDP1CYP2C9 | |
| SCHEMBL5658529 | 0.68 | TDP1 (0.69) | LMNASMN1; SMN2TDP1CYP2C9HPGD | |
| SCHEMBL3052007 | 0.68 | L3MBTL1 (0.78) | LMNASMN1; SMN2L3MBTL1TDP1HPGD | |
| SCHEMBL5658941 | 0.67 | IFNAR1 (0.65) | LMNASMN1; SMN2TDP1CYP2C9HPGD | |
| SCHEMBL3041196 | 0.66 | TDP1 (0.35) | L3MBTL1TDP1HPGD | |
| SCHEMBL2890325 | 0.66 | IFNAR1 (0.49) | LMNASMN1; SMN2TDP1HPGDRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8647878-B2 | Highly refractive immersion liquids and their use | CARL ZEISS AG (DE) | 2014-02-11 | — | — | US | disclosed |
| US-20100212547-A1 | Highly Refractive Immersion Liquids And Their Use | CARL ZEISS AG (DE) | 2010-08-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100212547-A1 | Highly Refractive Immersion Liquids And Their Use | NR4A3, NR2E3, NR4A1 | LMNA 2361/4885SMN1; SMN2 3042/4885L3MBTL1 2996/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.