Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.51 |
| ▸ | HTR3B | O95264 | 1/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.51 |
| ▸ | HTR3A | P46098 | 1/20 | 0.51 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.51 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9380858 | 0.85 | HTR3E (0.53) | L3MBTL1HTR3EHTR3BADRB1HTR3A | |
| SCHEMBL161063 | 0.84 | CYP3A4 (0.50) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL519497 | 0.81 | ALDH1A1 (0.56) | HTR3ALMNATSHRSMN1; SMN2KMT2A | |
| SCHEMBL12265053 | 0.81 | L3MBTL1 (0.57) | L3MBTL1HTR3EHTR3BADRB1HTR3A | |
| SCHEMBL21466082 | 0.81 | HTR3E (0.59) | L3MBTL1HTR3EHTR3BADRB1HTR3A | |
| SCHEMBL28599511 | 0.80 | HTR3E (0.73) | L3MBTL1HTR3EHTR3BADRB1HTR3A | |
| SCHEMBL29656856 | 0.80 | HTR3E (0.73) | L3MBTL1HTR3EHTR3BADRB1HTR3A | |
| SCHEMBL13246064 | 0.79 | ESR2 (0.47) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL28954366 | 0.79 | TRIM24 (0.52) | L3MBTL1LMNATSHRSMN1; SMN2KMT2A | |
| SCHEMBL28101787 | 0.79 | LTA4H (0.48) | HTR3EHTR3BHTR3AHTR3DHTR3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130237705-A1 | METHOD FOR MANUFACTURE OF 2-OXOIMIDAZOLIDINES | PETERSON JOHN R (US) | 2013-09-12 | — | — | US | disclosed |
| US-8431699-B2 | Method for manufacture of 2-oxoimidazolidines | Vertichem Corporation (CA) | 2013-04-30 | — | — | US | disclosed |
| US-8431699-B2 | Method for manufacture of 2-oxoimidazolidines | Vertichem Corporation (CA) | 2013-04-30 | — | — | US | disclosed |
| WO-2010099518-A2 | METHOD FOR MANUFACTURE OF 2-OXOIMIDAZOLIDINES | THESIS CHEMISTRY, LLC (US) | 2010-09-02 | — | — | WO | disclosed |
| WO-2010099518-A2 | METHOD FOR MANUFACTURE OF 2-OXOIMIDAZOLIDINES | THESIS CHEMISTRY, LLC (US) | 2010-09-02 | — | — | WO | disclosed |
| US-20100222588-A1 | Method for Manufacture of 2-Oxoimidazolidines | THESIS CHEMISTRY, LLC (US) | 2010-09-02 | — | — | US | disclosed |
| US-20100222588-A1 | Method for Manufacture of 2-Oxoimidazolidines | THESIS CHEMISTRY, LLC (US) | 2010-09-02 | — | — | US | disclosed |
| US-20100222588-A1 | Method for Manufacture of 2-Oxoimidazolidines | THESIS CHEMISTRY, LLC (US) | 2010-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130237705-A1 | METHOD FOR MANUFACTURE OF 2-OXOIMIDAZOLIDINES | ODC1, NISCH, IMPDH2 | L3MBTL1 4590/4885HTR3E 4513/4885HTR3B 3605/4885 |
| US-20100222588-A1 | Method for Manufacture of 2-Oxoimidazolidines | ODC1, CBR3, CBR1 | L3MBTL1 2067/4885HTR3E 4173/4885HTR3B 3717/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.