Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | XBP1 | P17861 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.42 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.42 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.42 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MMP3 | P08254 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2220603 | 1.00 | MEN1 (0.45) | MEN1KMT2ANPC1RAB9AMAPK1 | |
| SCHEMBL3047727 | 0.83 | HCRTR2 (0.45) | MEN1KMT2ARAB9AMAPTSMN1; SMN2 | |
| SCHEMBL7936084 | 0.83 | HCRTR2 (0.45) | MEN1KMT2ARAB9AMAPTSMN1; SMN2 | |
| SCHEMBL2339082 | 0.83 | MMP2 (0.50) | MEN1KMT2ANPC1RAB9AHTT | |
| SCHEMBL11204276 | 0.82 | PDK1 (0.46) | MEN1KMT2ANPC1RAB9AMAPK1 | |
| SCHEMBL636085 | 0.81 | RAB9A (0.44) | MEN1KMT2ANPC1RAB9AHTT | |
| SCHEMBL13224065 | 0.80 | MMP2 (0.50) | MEN1KMT2ANPC1RAB9AHTT | |
| SCHEMBL3042876 | 0.80 | MMP2 (0.50) | MEN1KMT2ANPC1RAB9AHTT | |
| SCHEMBL13336876 | 0.78 | MEN1 (0.47) | MEN1KMT2ANPC1RAB9AMAPK1 | |
| SCHEMBL2221800 | 0.78 | MMP2 (0.50) | MEN1KMT2ARAB9AMAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2358736-A1 | THERAPEUTIC ANTIVIRAL PEPTIDES | Intermune, Inc. (US) | 2011-08-24 | — | — | EP | disclosed |
| US-20110178107-A1 | HCV PROTEASE INHIBITORS | TAIGEN BIOTECHNOLOGY CO., LTD. (TW) | 2011-07-21 | — | — | US | disclosed |
| US-20100119479-A1 | THERAPEUTIC ANTIVIRAL PEPTIDES | INTERMUNE, INC. (US) | 2010-05-13 | — | — | US | disclosed |
| WO-2010045266-A1 | THERAPEUTIC ANTIVIRAL PEPTIDES | INTERMUNE, INC. (US) | 2010-04-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110178107-A1 | HCV PROTEASE INHIBITORS | HAVCR2, RNASE1, SERPINB1 | MEN1 4519/4885KMT2A 3358/4885NPC1 365/4885 |
| US-20100119479-A1 | THERAPEUTIC ANTIVIRAL PEPTIDES | SARS1, VIP, MAVS | MEN1 4087/4885KMT2A 4691/4885NPC1 525/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.