Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMBS | P08397 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.34 |
| ▸ | PNMT | P11086 | 1/20 | 0.32 |
| ▸ | G6PD | P11413 | 1/20 | 0.32 |
| ▸ | IDE | P14735 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25488568 | 0.78 | CA2 (0.44) | HMBSNOTUMTDO2 | |
| SCHEMBL28326197 | 0.76 | PTGS2 (0.36) | TDO2ENPP2PTGS2PNMTG6PD | |
| SCHEMBL28177607 | 0.76 | LMNA (0.36) | TDO2ENPP2PTGS2PNMT | |
| SCHEMBL17850509 | 0.73 | ENPP2 (0.31) | TDO2ENPP2PTGS2 | |
| SCHEMBL17591361 | 0.73 | SMN1; SMN2 (0.32) | TDO2ENPP2SMN1; SMN2 | |
| SCHEMBL9674035 | 0.72 | PKM (0.52) | TDO2MAPK1ENPP2PTGS2 | |
| SCHEMBL15067166 | 0.72 | ALDH1A1 (0.43) | TDO2MAPK1 | |
| SCHEMBL27827249 | 0.70 | ALDH1A1 (0.31) | — | |
| SCHEMBL1334156 | 0.68 | ENPP2 (0.48) | ENPP2PTGS2G6PDIDESMN1; SMN2 | |
| SCHEMBL13589497 | 0.67 | TSHR (0.53) | TDO2ENPP2PTGS2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116249697-A | Bicycloheptane pyrrolidine orexin receptor agonists | 默沙东有限责任公司 | 2023-06-09 | — | — | CN | disclosed |