SCHEMBL30478103

SCHEMBL30478103

CC(C)COc1ccc(Cn2nc(N3CCCCC3)cc2CC2CC2)cc1

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 1/20 0.36
HRH3 Q9Y5N1 8/20 0.35
LMNA P02545 2/20 0.35
TSHR P16473 2/20 0.35
ALDH1A1 P00352 1/20 0.35
MAPT P10636 1/20 0.35
THRB P10828 1/20 0.35
KMT2A Q03164 2/20 0.35
POLB P06746 1/20 0.35
MEN1 O00255 1/20 0.35
HTT P42858 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
FAAH O00519 1/20 0.34
CYP2D6 P10635 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30478094 0.84 MEN1 (0.41) LTA4HHRH3LMNATSHRALDH1A1
SCHEMBL30478119 0.82 SLC16A3 (0.38) LTA4HHRH3LMNATSHRALDH1A1
SCHEMBL30478116 0.81 LMNA (0.36) LTA4HHRH3LMNATSHRALDH1A1
SCHEMBL29024482 0.79 HTR2A (0.40) HRH3
SCHEMBL29024488 0.77 ABL1 (0.39) FAAH
SCHEMBL30478109 0.73 LTA4H (0.36) LTA4HHRH3LMNATSHRALDH1A1
SCHEMBL29024481 0.71 HTR2A (0.42) HRH3
SCHEMBL30478110 0.71 SLC16A3 (0.43) LTA4HHRH3LMNATSHRALDH1A1
SCHEMBL29024489 0.69 ABL1 (0.39)
SCHEMBL30478104 0.67 FAAH (0.37) LTA4HHRH3LMNAMAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116354925-A Pyrazole derivatives and use thereof 江苏恩华药业股份有限公司 2023-06-30 CN disclosed