SCHEMBL30480935

SCHEMBL30480935

N#Cc1ccc(Cl)c(F)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
VCAM1 P19320 1/20 0.48
KIF11 P52732 1/20 0.39
AR P10275 2/20 0.39
MAOA P21397 1/20 0.38
MAOB P27338 1/20 0.38
CYP11B1 P15538 2/20 0.37
EGLN2 Q96KS0 3/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
S1PR4 O95977 1/20 0.37
S1PR1 P21453 1/20 0.37
S1PR3 Q99500 1/20 0.37
SLC22A12 Q96S37 1/20 0.37
TRPV4 Q9HBA0 1/20 0.37
ALDH1A1 P00352 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
HTR2A P28223 2/20 0.36
KCNH2 Q12809 2/20 0.36
SLC6A4 P31645 1/20 0.36
CYP11B2 P19099 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL234592 1.00 VCAM1 (0.48) VCAM1KIF11ARMAOAMAOB
SCHEMBL233380 0.82 VCAM1 (0.44) VCAM1KIF11ARMAOAMAOB
SCHEMBL31195830 0.82 VCAM1 (0.44) VCAM1KIF11ARMAOAMAOB
SCHEMBL16136517 0.79 VCAM1 (0.50) VCAM1ARMAOAMAOBCA1
SCHEMBL29416796 0.78 EGLN2 (0.44) KIF11CYP11B1EGLN2CA2ALDH1A1
SCHEMBL229147 0.78 EGLN2 (0.44) KIF11CYP11B1EGLN2CA2ALDH1A1
SCHEMBL825866 0.78 VCAM1 (0.53) VCAM1ARMAOAMAOBCA1
SCHEMBL34471889 0.78 PSEN1 (0.48) VCAM1CYP11B1EGLN2S1PR4S1PR1
SCHEMBL12721370 0.77 IMPDH2 (0.39) KIF11CYP11B1EGLN2CA2ALDH1A1
SCHEMBL16955681 0.77 RAPGEF4 (0.34) SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116583522-A Indolo [3.2.1-JK ] carbazole-6-carbonitrile derivatives as blue fluorescent emitters for use in OLEDs 默克专利有限公司 2023-08-11 CN disclosed