SCHEMBL233380

SCHEMBL233380

N#Cc1ccc(F)c(Cl)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
VCAM1 P19320 1/20 0.44
AR P10275 2/20 0.42
MAOA P21397 1/20 0.42
MAOB P27338 1/20 0.42
FLT1 P17948 1/20 0.40
FLT4 P35916 1/20 0.40
KDR P35968 1/20 0.40
PDK1 Q15118 1/20 0.40
PDK2 Q15119 1/20 0.40
PDK3 Q15120 1/20 0.40
PDK4 Q16654 1/20 0.40
GRM5 P41594 1/20 0.40
KIF11 P52732 1/20 0.39
MEN1 O00255 1/20 0.38
ALDH1A1 P00352 1/20 0.38
MAPT P10636 1/20 0.38
HTT P42858 1/20 0.38
KMT2A Q03164 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
EGLN2 Q96KS0 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31195830 1.00 VCAM1 (0.44) VCAM1ARMAOAMAOBFLT1
SCHEMBL2902333 0.84 KIF11 (0.54) MAOAMAOBKIF11TDO2HSD11B1
SCHEMBL30480935 0.82 VCAM1 (0.48) VCAM1ARMAOAMAOBPDK1
SCHEMBL234592 0.82 VCAM1 (0.48) VCAM1ARMAOAMAOBPDK1
4-Hydroxybenzaldehyde SCHEMBL27549492 0.79 ALDH5A1 (0.46) MAOAMAOBFLT1FLT4KDR
SCHEMBL22115304 0.79 GABRG2 (0.52) PDK2SLC22A12
SCHEMBL30712417 0.79 GABRG2 (0.52) PDK2SLC22A12
SCHEMBL1477679 0.79 CYP11B1 (0.43) GRM5
SCHEMBL825866 0.78 VCAM1 (0.53) VCAM1ARMAOAMAOBFLT1
SCHEMBL29416796 0.78 EGLN2 (0.44) GRM5KIF11ALDH1A1EGLN2CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 547 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111668481-B Preparation method of metal aluminum secondary battery with multi-group organic micromolecules as positive electrode 北京科技大学 2021-12-03 CN claimed
CN-111668481-A Preparation method of metal aluminum secondary battery with multi-group organic micromolecules as positive electrode 北京科技大学 2020-09-15 CN claimed
US-5897940-A Ink jet transparencies XEROX CORPORATION (US) 1999-04-27 US claimed
US-5744273-A Laminatable backing substrates containing fluoro compounds for improved toner flow XEROX CORPORATION (US) 1998-04-28 US claimed
JP-6072980-A None JP disclosed
WO-2026099466-A1 TARGETED PROTEIN DEGRADATION MONTE ROSA THERAPEUTICS AG (CH) 2026-05-15 WO disclosed
US-12570799-B2 Crystalline polyethernitrile TORAY INDUSTRIES, INC. (JP) 2026-03-10 US disclosed
EP-4678641-A1 QUINOLINONE COMPOUND AND NAPHTHYRIDINONE COMPOUND AND USE THEREOF Shanghai Helioson Pharmaceutical Co., Ltd. (CN) 2026-01-14 EP disclosed
US-12378218-B2 Cyclopentane compounds DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD. (CN) 2025-08-05 US disclosed
US-20250243183-A1 IMIDAZOLYL PYRIMIDINYLAMINE COMPOUNDS AS CDK2 INHIBITORS INCYTE CORPORATION 2025-07-31 US disclosed
EP-4570313-A2 CYANOTRIAZOLE COMPOUNDS Otsuka Pharmaceutical Co., Ltd. (JP) 2025-06-18 EP disclosed
US-12312331-B2 Imidazolyl pyrimidinylamine compounds as CDK2 inhibitors INCYTE CORPORATION (US) 2025-05-27 US disclosed
JP-H0672980-A PRODUCTION OF 3,4-DIFLUOROBENZONITRILE ASAHI GLASS CO LTD 1994-03-15 JP disclosed
EP-0270964-B1 PROCESS FOR OBTAINING SUBSTITUTED FLUOROBENZENES BAYER AG (DE) 1992-07-08 EP disclosed
US-4868347-A SOLVENT EXTRACTION BAYER AKTIENGESELLSCHAFT (DE) 1989-09-19 US disclosed
US-4704483-A FLUORINATION WITH POTASSIUM FLUORIDE OCCIDENTAL CHEMICAL CORPORATION (US) 1987-11-03 US disclosed
US-4582948-A VAPOR PHASE CHLORO-DENITRATION REACTION OCCIDENTAL CHEMICAL CORPORATION (US) 1986-04-15 US disclosed
EP-0159388-A2 Preparation of nuclear chlorinated compounds OCCIDENTAL CHEMICAL CORPORATION (US) 1985-10-30 EP disclosed
US-4470930-A Preparation of nuclear chlorinated aromatic compounds OCCIDENTAL CHEMICAL CORPORATION (US) 1984-09-11 US disclosed
US-4351777-A Preparation of fluorobenzonitriles RHONE-POULENC INDUSTRIES (FR) 1982-09-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12378218-B2 Cyclopentane compounds CYP11B2, CYP11B1, SQLE VCAM1 1842/4885AR 2420/4885MAOA 1770/4885
US-12312331-B2 Imidazolyl pyrimidinylamine compounds as CDK2 inhibitors CDK2, CDK4, CDK2AP2 VCAM1 3711/4885AR 2395/4885MAOA 3883/4885
US-12570799-B2 Crystalline polyethernitrile AR, NR5A1, ESRRA VCAM1 3399/4885AR 1/4885MAOA 4330/4885
US-20250243183-A1 IMIDAZOLYL PYRIMIDINYLAMINE COMPOUNDS AS CDK2 INHIBITORS CDK2, CDK4, CDK2AP2 VCAM1 3711/4885AR 2395/4885MAOA 3883/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.