Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 1/20 | 0.48 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.37 |
| ▸ | EGLN2 | Q96KS0 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.37 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30480935 | 1.00 | VCAM1 (0.48) | VCAM1KIF11ARMAOAMAOB | |
| SCHEMBL233380 | 0.82 | VCAM1 (0.44) | VCAM1KIF11ARMAOAMAOB | |
| SCHEMBL31195830 | 0.82 | VCAM1 (0.44) | VCAM1KIF11ARMAOAMAOB | |
| SCHEMBL16136517 | 0.79 | VCAM1 (0.50) | VCAM1ARMAOAMAOBCA1 | |
| SCHEMBL29416796 | 0.78 | EGLN2 (0.44) | KIF11CYP11B1EGLN2CA2ALDH1A1 | |
| SCHEMBL229147 | 0.78 | EGLN2 (0.44) | KIF11CYP11B1EGLN2CA2ALDH1A1 | |
| SCHEMBL825866 | 0.78 | VCAM1 (0.53) | VCAM1ARMAOAMAOBCA1 | |
| SCHEMBL34471889 | 0.78 | PSEN1 (0.48) | VCAM1CYP11B1EGLN2S1PR4S1PR1 | |
| SCHEMBL12721370 | 0.77 | IMPDH2 (0.39) | KIF11CYP11B1EGLN2CA2ALDH1A1 | |
| SCHEMBL16955681 | 0.77 | RAPGEF4 (0.34) | SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 165 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119306598-A | Catalyst composition, application thereof and synthetic method of cyhalofop-butyl | 江苏省农用激素工程技术研究中心有限公司 | 2025-01-14 | — | — | CN | claimed |
| EP-0635486-B1 | Process for the preparation of fluorobenzonitriles | CLARIANT GMBH (DE) | 1998-12-09 | — | — | EP | claimed |
| US-5466859-A | Process for preparing fluorobenzonitriles | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-11-14 | — | — | US | claimed |
| EP-0635486-A2 | Process for the preparation of fluorobenzonitriles | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-01-25 | — | — | EP | claimed |
| EP-3704096-B1 | MODULATORS OF THE INTEGRATED STRESS PATHWAY | CALICO LIFE SCIENCES LLC (US) | 2026-04-22 | — | — | EP | disclosed |
| EP-4291183-B1 | OXADIAZOLYL DIHYDROPYRANO[2,3-B]PYRIDINE INHIBITORS OF HIPK2 FOR TREATING KIDNEY FIBROSIS | ICAHN SCHOOL MED MOUNT SINAI (US) | 2026-04-08 | — | — | EP | disclosed |
| US-12570799-B2 | Crystalline polyethernitrile | TORAY INDUSTRIES, INC. (JP) | 2026-03-10 | — | — | US | disclosed |
| CN-119306598-B | Catalyst composition, application thereof and synthetic method of cyhalofop-butyl | 江苏省农用激素工程技术研究中心有限公司 | 2025-12-12 | — | — | CN | disclosed |
| EP-4565589-A2 | OXYGEN-CONTAINING HETEROCYCLIC COMPOUND AND USE THEREOF | Icahn School of Medicine at Mount Sinai (US) | 2025-06-11 | — | — | EP | disclosed |
| US-20250179084-A1 | OXADIAZOLYL DIHYDROPYRANO[2,3-b]PYRIDINE INHIBITORS OF HIPK2 FOR TREATING KIDNEY FIBROSIS | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2025-06-05 | — | — | US | disclosed |
| US-20250145594-A1 | MODULATORS OF THE INTEGRATED STRESS PATHWAY | ABBVIE INC. | 2025-05-08 | — | — | US | disclosed |
| US-20250092208-A1 | POLYETHER NITRILE FILM AND METHOD FOR PRODUCING POLYETHER NITRILE FILM | TORAY INDUSTRIES, INC. (JP) | 2025-03-20 | — | — | US | disclosed |
| EP-0635486-A2 | Process for the preparation of fluorobenzonitriles | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-01-25 | — | — | EP | disclosed |
| EP-0456793-A1 | HALOPHENYL SUBSTITUTED HETEROCYCLIC DERIVATIVES. | MERCK PATENT GMBH (DE) | 1991-11-21 | — | — | EP | disclosed |
| WO-1991009016-A2 | HALOPHENYL SUBSTITUTED HETEROCYCLIC DERIVATIVES | MERCK PATENT GMBH (DE) | 1991-06-27 | — | — | WO | disclosed |
| WO-1991009016-A1 | HALOPHENYL SUBSTITUTED HETEROCYCLIC DERIVATIVES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1991-06-27 | — | — | WO | disclosed |
| US-4704483-A | FLUORINATION WITH POTASSIUM FLUORIDE | OCCIDENTAL CHEMICAL CORPORATION (US) | 1987-11-03 | — | — | US | disclosed |
| US-4582948-A | VAPOR PHASE CHLORO-DENITRATION REACTION | OCCIDENTAL CHEMICAL CORPORATION (US) | 1986-04-15 | — | — | US | disclosed |
| EP-0159388-A2 | Preparation of nuclear chlorinated compounds | OCCIDENTAL CHEMICAL CORPORATION (US) | 1985-10-30 | — | — | EP | disclosed |
| US-4470930-A | Preparation of nuclear chlorinated aromatic compounds | OCCIDENTAL CHEMICAL CORPORATION (US) | 1984-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250145594-A1 | MODULATORS OF THE INTEGRATED STRESS PATHWAY | ATF4, ATF1, DDIT3 | VCAM1 4474/4885KIF11 3720/4885AR 2402/4885 |
| US-12570799-B2 | Crystalline polyethernitrile | AR, NR5A1, ESRRA | VCAM1 3399/4885KIF11 2556/4885AR 1/4885 |
| US-20250179084-A1 | OXADIAZOLYL DIHYDROPYRANO[2,3-b]PYRIDINE INHIBITORS OF HIPK2 FOR TREATING KIDNEY FIBROSIS | HIPK2, HIPK3, HIPK1 | VCAM1 3528/4885KIF11 3214/4885AR 330/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.