Amiloxate

Amiloxate

SCHEMBL30480951

CCOc1ccc(C=CC(=O)O)c(CCC(C)C)c1.COc1ccc(C=CC(=O)OCCC(C)C)cc1

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.62
LMNA P02545 2/20 0.62
THRB P10828 1/20 0.45
ATM Q13315 1/20 0.45
PTGER4 P35408 1/20 0.44
PTGER3 P43115 1/20 0.44
PTGER2 P43116 1/20 0.44
MAOB P27338 1/20 0.43
SMN1; SMN2 Q16637 2/20 0.42
KDM4E B2RXH2 2/20 0.42
ALDH1A1 P00352 2/20 0.42
POLB P06746 1/20 0.42
KMT2A Q03164 3/20 0.39
MEN1 O00255 2/20 0.39
TAS1R3 Q7RTX0 1/20 0.39
TAS1R1 Q7RTX1 1/20 0.39
MAPT P10636 1/20 0.39
AKR1C3 P42330 1/20 0.39
AKR1C2 P52895 1/20 0.39
FDPS P14324 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Amiloxate SCHEMBL23114206 0.94 LMNA (0.69) TDP1LMNATHRBATMPTGER4
4-Methoxycinnamic Acid SCHEMBL19717829 0.86 THRB (0.58) TDP1LMNATHRBATMPTGER4
SCHEMBL2834266 0.84 ALDH1A1 (0.50) PTGER4PTGER3PTGER2SMN1; SMN2KDM4E
SCHEMBL2834265 0.84 ALDH1A1 (0.50) PTGER4PTGER3PTGER2SMN1; SMN2KDM4E
Amiloxate SCHEMBL1768923 0.83 LMNA (0.90) TDP1LMNATHRBATMSMN1; SMN2
SCHEMBL196086 0.80 PTGER4 (0.48) TDP1LMNATHRBATMPTGER4
SCHEMBL290383 0.80 PTGER4 (0.48) TDP1LMNATHRBATMPTGER4
SCHEMBL8075739 0.79 LMNA (0.76) TDP1LMNAMAOBSMN1; SMN2KDM4E
SCHEMBL22400703 0.79 LMNA (0.76) TDP1LMNAMAOBSMN1; SMN2KDM4E
Amiloxate SCHEMBL2228053 0.79 LMNA (1.00) TDP1LMNATHRBATMSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118695840-A UV filter composition comprising closed cell metal oxide particles 巴斯夫欧洲公司 2024-09-24 CN disclosed
CN-118574599-A UV filter compositions comprising hybrid metal oxide particles 巴斯夫欧洲公司 2024-08-30 CN disclosed
CN-111050742-B Water-based concentrated product forms of oil-soluble organic ultraviolet absorbers 巴斯夫欧洲公司 2023-06-30 CN disclosed