SCHEMBL2834266

SCHEMBL2834266

CCOc1ccc(C=CC(=O)O)c(CCC(C)C)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.50
KDM4E B2RXH2 3/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
GAA P10253 1/20 0.44
AKR1C3 P42330 1/20 0.44
AKR1C2 P52895 1/20 0.44
POLB P06746 1/20 0.44
HPGD P15428 2/20 0.41
TSHR P16473 2/20 0.41
HSD17B10 Q99714 2/20 0.41
CYP1A2 P05177 1/20 0.41
PTGER3 P43115 2/20 0.41
PTGDR Q13258 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
CYP1A1 P04798 1/20 0.39
CYP1B1 Q16678 1/20 0.39
PPARA Q07869 1/20 0.39
MAPT P10636 1/20 0.39
CA12 O43570 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2834265 1.00 ALDH1A1 (0.50) ALDH1A1KDM4ESMN1; SMN2GAAAKR1C3
SCHEMBL290383 0.87 PTGER4 (0.48) ALDH1A1KDM4ESMN1; SMN2GAAPTGER3
SCHEMBL196086 0.87 PTGER4 (0.48) ALDH1A1KDM4ESMN1; SMN2GAAPTGER3
Amiloxate SCHEMBL30480951 0.84 TDP1 (0.62) ALDH1A1KDM4ESMN1; SMN2AKR1C3AKR1C2
4-Methoxycinnamic Acid SCHEMBL19717829 0.82 THRB (0.58) SMN1; SMN2GAAAKR1C3AKR1C2PTGER3
SCHEMBL27733413 0.80 MIF (0.51) PTGER3CA12CA1CA2CA4
SCHEMBL27733409 0.80 MIF (0.51) PTGER3CA12CA1CA2CA4
Coumarinic Acid Methyl Ether SCHEMBL19717828 0.79 GAA (0.55) ALDH1A1KDM4ESMN1; SMN2GAACYP1A2
SCHEMBL10891531 0.77 PTGS2 (0.41) ALDH1A1KDM4ESMN1; SMN2GAAPTGER3
SCHEMBL28039182 0.76 KDM4E (0.57) ALDH1A1KDM4ESMN1; SMN2GAAAKR1C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070079446-A1 Stabilized body care products, household products, textiles and fabrics CIBA SPECIALTY CHEMICALS CORP. 2007-04-12 US claimed
CN-1902353-A Stabilized body care products, household products, textiles and fabrics CIBA SC HOLDING AG (CH) 2007-01-24 CN claimed
EP-1680541-A2 STABILIZED BODY CARE PRODUCTS, HOUSEHOLD PRODUCTS, TEXTILES AND FABRICS Ciba SC Holding AG (CH) 2006-07-19 EP claimed
WO-2005042828-A2 STABILIZED BODY CARE PRODUCTS, HOUSEHOLD PRODUCTS, TEXTILES AND FABRICS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2005-05-12 WO claimed
US-11918672-B2 Water based concentrated product forms of oil-soluble organic UV absorbers BASF SE (DE) 2024-03-05 US disclosed
WO-2023139038-A1 UV FILTER COMPOSITIONS COMPRISING HYBRID METAL OXIDE PARTICLES BASF SE (DE) 2023-07-27 WO disclosed
WO-2023139037-A1 UV FILTER COMPOSITIONS COMPRISING CLOSED-CELL METAL OXIDE PARTICLES BASF SE (DE) 2023-07-27 WO disclosed
CN-111050742-B Water-based concentrated product forms of oil-soluble organic ultraviolet absorbers 巴斯夫欧洲公司 2023-06-30 CN disclosed
US-20220183934-A1 SUNSCREEN COMPOSITIONS CONTAINING POROUS METAL OXIDE SPHERES BASF SE (DE) 2022-06-16 US disclosed
EP-3937883-A1 SUNSCREEN COMPOSITIONS CONTAINING POROUS METAL OXIDE SPHERES BASF SE (DE) 2022-01-19 EP disclosed
CN-113507915-A Sunscreen composition comprising porous metal oxide spheres 巴斯夫欧洲公司 2021-10-15 CN disclosed
US-20200337974-A1 WATER BASED CONCENTRATED PRODUCT FORMS OF OIL-SOLUBLE ORGANIC UV ABSORBERS BASF SE (DE) 2020-10-29 US disclosed
US-20070079446-A1 Stabilized body care products, household products, textiles and fabrics CIBA SPECIALTY CHEMICALS CORP. 2007-04-12 US disclosed
US-7008638-B2 Use of nanodispersions in cosmetic end formulations CIBA SPECIALTY CHEMICALS CORPORATION (US) 2006-03-07 US disclosed
US-20050191330-A1 Easily prepared carrier systems for wide range of active agents and oil soluble dyes; homogeneous ethanol and water clear liquid containing phospholipid, endcapped polyoxyethylene coemulsifier and lipophilic triglyceride; wide pH range CIBA SPECIALTY CHEMICALS CORP. 2005-09-01 US disclosed
US-6746666-B1 Micropigment mixture CIBA SPECIALTY CHEMICALS CORPORATION 2004-06-08 US disclosed
CN-1394135-A Use of microbially encapsulated materials in cosmetic end formulations CIBA SC HOLDING AG (CH) 2003-01-29 CN disclosed
US-20020155073-A1 Use of mixtures of micropigments for preventing tanning and for lightening skin and hair FANKHAUSER PETER (CH) 2002-10-24 US disclosed
US-20020106390-A1 Use of nanodispersions in cosmetic end formulations HUGLIN DIETMAR (DE) 2002-08-08 US disclosed
CN-1281695-A Microfine pigment mixture and its application for preventing skin from tanning and making skin and hair passess glass CIBA SC HOLDING AG (CH) 2001-01-31 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070079446-A1 Stabilized body care products, household products, textiles and fabrics CUTA, NISCH, DSC1 ALDH1A1 1122/4885KDM4E 1682/4885SMN1; SMN2 864/4885
US-20220183934-A1 SUNSCREEN COMPOSITIONS CONTAINING POROUS METAL OXIDE SPHERES SDHB, SDHA, MCM5 ALDH1A1 596/4885KDM4E 1341/4885SMN1; SMN2 3538/4885
US-20050191330-A1 Easily prepared carrier systems for wide range of active agents and oil soluble dyes; homogeneous ethanol and water clear liquid containing phospholipid, endcapped polyoxyethylene coemulsifier and lipophilic triglyceride; wide pH range LIPA, CETP, LIPC ALDH1A1 216/4885KDM4E 4131/4885SMN1; SMN2 4239/4885
US-20020155073-A1 Use of mixtures of micropigments for preventing tanning and for lightening skin and hair MITF, TYR, CUTA ALDH1A1 1051/4885KDM4E 3178/4885SMN1; SMN2 4484/4885
US-20020106390-A1 Use of nanodispersions in cosmetic end formulations NPC1L1, LIPA, CUTA ALDH1A1 414/4885KDM4E 4700/4885SMN1; SMN2 3919/4885
US-20200337974-A1 WATER BASED CONCENTRATED PRODUCT FORMS OF OIL-SOLUBLE ORGANIC UV ABSORBERS SSRP1, ACMSD, TST ALDH1A1 1958/4885KDM4E 4270/4885SMN1; SMN2 4264/4885
US-11918672-B2 Water based concentrated product forms of oil-soluble organic UV absorbers TST, SSRP1, SUPT16H ALDH1A1 1270/4885KDM4E 4529/4885SMN1; SMN2 4050/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.