Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | USP2 | O75604 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | KIF11 | P52732 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.44 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.43 |
| ▸ | CDK4 | P11802 | 2/20 | 0.43 |
| ▸ | CCND1 | P24385 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4420525 | 0.79 | DAO (0.32) | ALDH1A1HSD17B10HPGDUSP2MEN1 | |
| SCHEMBL28669933 | 0.77 | ALDH1A1 (0.55) | ALDH1A1HSD17B10HPGDUSP2MEN1 | |
| SCHEMBL30494604 | 0.75 | ALDH1A1 (0.53) | ALDH1A1HSD17B10HPGDUSP2MEN1 | |
| SCHEMBL7915531 | 0.75 | ALDH1A1 (0.66) | ALDH1A1HSD17B10HPGDUSP2MEN1 | |
| SCHEMBL3433646 | 0.75 | ALDH1A1 (0.53) | ALDH1A1HSD17B10HPGDUSP2MEN1 | |
| SCHEMBL29275406 | 0.75 | ALDH1A1 (0.53) | ALDH1A1HSD17B10HPGDUSP2MEN1 | |
| SCHEMBL15902077 | 0.74 | DAO (0.43) | ALDH1A1HSD17B10HPGDMEN1KMT2A | |
| Iodide SCHEMBL27218977 | 0.73 | ALDH1A1 (0.64) | ALDH1A1HSD17B10HPGDUSP2MEN1 | |
| SCHEMBL29513389 | 0.73 | HSD17B10 (1.00) | ALDH1A1HSD17B10HPGDUSP2MEN1 | |
| SCHEMBL633784 | 0.73 | ALDH1A1 (0.56) | ALDH1A1HSD17B10HPGDUSP2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1986701-B1 | OPTICAL AGENTS FOR USE IN SURGERY | MALLINCKRODT LLC (US) | 2012-06-13 | — | — | EP | claimed |
| US-11351274-B2 | Methods of using optical agents | MEDIBEACON INC. (US) | 2022-06-07 | — | — | US | disclosed |
| US-11185597-B2 | Process for using optical agents | MEDIBEACON, INC. (US) | 2021-11-30 | — | — | US | disclosed |
| US-10695445-B2 | Methods of using optical agents | MEDIBEACON INC. (US) | 2020-06-30 | — | — | US | disclosed |
| US-20190192695-A1 | PROCESS FOR USING OPTICAL AGENTS | MALLINCKRODT LLC | 2019-06-27 | — | — | US | disclosed |
| US-20190192696-A1 | METHODS OF USING OPTICAL AGENTS | MALLINCKRODT LLC | 2019-06-27 | — | — | US | disclosed |
| US-20190022256-A1 | METHODS OF USING OPTICAL AGENTS | MALLINCKRODT LLC | 2019-01-24 | — | — | US | disclosed |
| US-10137207-B2 | Methods of using optical agents | MEDIBEACON, INC. (US) | 2018-11-27 | — | — | US | disclosed |
| US-9283288-B2 | Methods of using optical agents | MEDIBEACON, INC. (US) | 2016-03-15 | — | — | US | disclosed |
| US-20160045619-A1 | METHODS OF USING OPTICAL AGENTS | MALLINCKRODT INC. | 2016-02-18 | — | — | US | disclosed |
| EP-1986701-B1 | OPTICAL AGENTS FOR USE IN SURGERY | MALLINCKRODT LLC (US) | 2012-06-13 | — | — | EP | disclosed |
| US-20080312539-A1 | Methods of Using Optical Agents | MEDIBEACON, INC. | 2008-12-18 | — | — | US | disclosed |
| EP-1986701-A2 | PROCESS FOR USING OPTICAL AGENTS | MALLINCKRODT, INC. (US) | 2008-11-05 | — | — | EP | disclosed |
| WO-2007106142-A2 | PROCESS FOR USING OPTICAL AGENTS | MALLINCKRODT INC. (US) | 2007-09-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160045619-A1 | METHODS OF USING OPTICAL AGENTS | REN, ATP6V1B1, VHL | ALDH1A1 2024/4885HSD17B10 4862/4885HPGD 2339/4885 |
| US-10695445-B2 | Methods of using optical agents | REN, ATP6V1B1, VHL | ALDH1A1 2024/4885HSD17B10 4862/4885HPGD 2339/4885 |
| US-20190022256-A1 | METHODS OF USING OPTICAL AGENTS | REN, ATP6V1B1, VHL | ALDH1A1 2024/4885HSD17B10 4862/4885HPGD 2339/4885 |
| US-20190192695-A1 | PROCESS FOR USING OPTICAL AGENTS | REN, ATP6V1B1, VHL | ALDH1A1 1866/4885HSD17B10 4836/4885HPGD 2649/4885 |
| US-11185597-B2 | Process for using optical agents | REN, ATP6V1B1, VHL | ALDH1A1 1866/4885HSD17B10 4836/4885HPGD 2649/4885 |
| US-11351274-B2 | Methods of using optical agents | REN, ATP6V1B1, VHL | ALDH1A1 2024/4885HSD17B10 4862/4885HPGD 2339/4885 |
| US-20190192696-A1 | METHODS OF USING OPTICAL AGENTS | REN, ATP6V1B1, VHL | ALDH1A1 2024/4885HSD17B10 4862/4885HPGD 2339/4885 |
| US-10137207-B2 | Methods of using optical agents | REN, ATP6V1B1, VHL | ALDH1A1 2024/4885HSD17B10 4862/4885HPGD 2339/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.