Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | CASP6 | P55212 | 1/20 | 0.34 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.31 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21505363 | 0.83 | TRIM24 (0.46) | NSD2CASP6TRIM24TRIM33ALDH1A1 | |
| SCHEMBL30503296 | 0.73 | ALDH1A1 (0.38) | NSD2CASP6ALDH1A1 | |
| SCHEMBL1991557 | 0.73 | CASP6 (0.50) | NSD2CASP6ALDH1A1 | |
| SCHEMBL17796068 | 0.73 | NSD2 (0.36) | NSD2CASP6ALDH1A1 | |
| SCHEMBL23628714 | 0.72 | CYP11B2 (0.40) | ALDH1A1 | |
| SCHEMBL21505366 | 0.72 | LMNA (0.34) | ALDH1A1 | |
| SCHEMBL4575968 | 0.71 | ALDH1A1 (0.39) | ALDH1A1 | |
| SCHEMBL1990688 | 0.67 | CYP1A2 (0.49) | ALDH1A1 | |
| SCHEMBL24179779 | 0.66 | ALDH1A1 (0.41) | NSD2TRIM24TRIM33ALDH1A1 | |
| SCHEMBL12087690 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946546-B1 | PYRIDIN-2-YL-METHYLAMINE DERIVATIVES, METHOD OF PREPARING AND APPLICATION AS MEDICINE | PF MEDICAMENT (FR) | 2003-06-25 | — | — | EP | disclosed |
| US-6020345-A | Pyridin-2-yl-methylamine derivatives, method of preparing and application as medicine | PIERRE FABRE MEDICAMENT (FR) | 2000-02-01 | — | — | US | disclosed |