Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.62 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.54 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1459903 | 0.89 | ALDH1A1 (0.62) | L3MBTL1ALOX5ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL12795836 | 0.88 | L3MBTL1 (0.57) | L3MBTL1ALOX5HSD11B1HSP90AA1MGLL | |
| SCHEMBL1750871 | 0.86 | L3MBTL1 (0.56) | L3MBTL1ALOX5HSD11B1HSP90AA1MGLL | |
| SCHEMBL25575682 | 0.85 | L3MBTL1 (0.54) | L3MBTL1ALOX5HSD11B1HSP90AA1MGLL | |
| SCHEMBL6401435 | 0.84 | L3MBTL1 (0.53) | L3MBTL1ALOX5HSD11B1HSP90AA1MGLL | |
| SCHEMBL23601592 | 0.82 | L3MBTL1 (0.46) | L3MBTL1ALOX5 | |
| SCHEMBL5605334 | 0.80 | POLB (0.46) | L3MBTL1HSP90AA1HSD17B10 | |
| SCHEMBL30516650 | 0.80 | ALOX5 (0.55) | ALOX5MGLLALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL25366082 | 0.80 | ALOX5 (0.55) | ALOX5MGLLALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL12879707 | 0.80 | L3MBTL1 (0.51) | L3MBTL1ALOX5HSD11B1HSP90AA1MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021003295-A1 | MODULATORS OF HSD17B13 AND METHODS OF USE THEREOF | REGENERON PHARMACEUTICALS, INC. (US) | 2021-01-07 | — | — | WO | disclosed |
| US-20170362201-A1 | COT MODULATORS AND METHODS OF USE THEREOF | GILEAD SCIENCES, INC. | 2017-12-21 | — | — | US | disclosed |
| US-9815818-B2 | Cot modulators and methods of use thereof | GILEAD SCIENCES, INC. (US) | 2017-11-14 | — | — | US | disclosed |
| US-20170008873-A1 | COT MODULATORS AND METHODS OF USE THEREOF | GILEAD SCIENCES, INC. | 2017-01-12 | — | — | US | disclosed |
| EP-0534359-A1 | Process for preparing arylene sulfide polymers | PHILLIPS PETROLEUM COMPANY (US) | 1993-03-31 | — | — | EP | disclosed |
| US-5110902-A | High molecular weight polythioether-sulfones | PHILLIPS PETROLEUM COMPANY (US) | 1992-05-05 | — | — | US | disclosed |
| US-5086163-A | High molecular weight polymers formed by contacting dihaloaromatic sulfone with complex of alkali metal aminoalkanoate and alkalimetal hydrosulfide | PHILLIPS PETROLEUM COMPANY (US) | 1992-02-04 | — | — | US | disclosed |
| US-5023315-A | Reacting dihaloaromatic component with complex of lactams, alkali hydroxide and sulfur source, such as alkali metal bisulfide, thiolactam or hydrogen sulfide; whiteness, purity | PHILLIPS PETEROLEUM COMPANY (US) | 1991-06-11 | — | — | US | disclosed |
| US-5015725-A | Heat resistant thermoplastic resins for electrical components, aircraft or automobile parts, protective coatings | PHILLIPS PETROLEUM COMPANY (US) | 1991-05-14 | — | — | US | disclosed |
| EP-0309955-A1 | Aromatic sulfide/sulfone polymer production | PHILLIPS PETROLEUM COMPANY (US) | 1989-04-05 | — | — | EP | disclosed |
| EP-0039508-B1 | A PROCESS FOR PREPARING ALKALI METAL AMINO ALKANOATES AND USE OF SAME | PHILLIPS PETROLEUM COMPANY (US) | 1984-03-07 | — | — | EP | disclosed |
| US-4371706-A | SALT FORMATION, HYDROLYSIS | PHILLIPS PETROLEUM COMPANY (US) | 1983-02-01 | — | — | US | disclosed |
| US-4324886-A | POLYMERIZATION OF POLYHALO AROMATIC COMPOUND AND HYDROGEN SULFIDE | PHILLIPS PETROLEUM COMPANY (US) | 1982-04-13 | — | — | US | disclosed |
| EP-0039508-A1 | A process for preparing alkali metal amino alkanoates and use of same | PHILLIPS PETROLEUM COMPANY (US) | 1981-11-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170362201-A1 | COT MODULATORS AND METHODS OF USE THEREOF | BRDT, THRB, HCCS | L3MBTL1 3141/4885ALOX5 668/4885HSD11B1 4061/4885 |
| US-20170008873-A1 | COT MODULATORS AND METHODS OF USE THEREOF | BRDT, THRB, HCCS | L3MBTL1 3141/4885ALOX5 668/4885HSD11B1 4061/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.