Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR4 | P46093 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | ACKR3 | P25106 | 3/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.42 |
| ▸ | WNT3A | P56704 | 1/20 | 0.42 |
| ▸ | VEGFA | P15692 | 1/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30520640 | 0.88 | MEN1 (0.50) | GPR4MEN1MAPTTSHRKMT2A | |
| SCHEMBL115666 | 0.87 | GPR119 (0.44) | GPR4GPR119POLBCHRM2CHRM4 | |
| SCHEMBL14190953 | 0.83 | MEN1 (0.50) | GPR4MEN1MAPTTSHRKMT2A | |
| SCHEMBL2850833 | 0.81 | KDM1A (0.48) | MEN1KMT2AGPR119POLBCHRM2 | |
| SCHEMBL402526 | 0.80 | HTR1A (0.53) | — | |
| SCHEMBL4572803 | 0.80 | SIGMAR1 (0.48) | MEN1MAPTKMT2ACHRM2CHRM4 | |
| SCHEMBL22800905 | 0.80 | SIGMAR1 (0.48) | MEN1MAPTKMT2ASMN1; SMN2CHRM2 | |
| SCHEMBL4832556 | 0.80 | GPR119 (0.57) | MEN1KMT2AGPR119POLBCHRM2 | |
| SCHEMBL3708001 | 0.80 | HTR2A (0.52) | CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL2379018 | 0.80 | THRB (0.52) | MEN1KMT2ASMN1; SMN2CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080103123-A1 | New compounds | BIOVITRUM (SE) | 2008-05-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080103123-A1 | New compounds | GPR119, GPR139, GPR180 | GPR4 11/4885MEN1 2409/4885MAPT 1005/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.