Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4562511 | 1.00 | ACHE (0.44) | ACHEL3MBTL1SMN1; SMN2KMT2ANPC1 | |
| SCHEMBL10165952 | 0.78 | ACHE (0.46) | ACHEL3MBTL1SMN1; SMN2KMT2ANPC1 | |
| SCHEMBL6035271 | 0.77 | ACHE (0.50) | ACHEL3MBTL1SMN1; SMN2KMT2ANPC1 | |
| SCHEMBL4950654 | 0.77 | HTR1A (0.50) | ACHEL3MBTL1SMN1; SMN2KMT2ANPC1 | |
| SCHEMBL31666386 | 0.77 | HTR1A (0.50) | ACHEL3MBTL1SMN1; SMN2KMT2ANPC1 | |
| SCHEMBL144308 | 0.75 | ACHE (0.68) | ACHEL3MBTL1KMT2ATDP1TP53 | |
| SCHEMBL29352952 | 0.75 | ACHE (0.68) | ACHEL3MBTL1KMT2ATDP1TP53 | |
| Hydrochloric Acid SCHEMBL27494639 | 0.74 | ACHE (0.43) | ACHEL3MBTL1SMN1; SMN2KMT2ANPC1 | |
| Hydrochloric Acid SCHEMBL27516546 | 0.74 | LMNA (0.44) | ACHETDP1ALDH1A1CYP3A4GAA | |
| Hydrochloric Acid SCHEMBL4509700 | 0.74 | ALDH1A1 (0.39) | ACHEL3MBTL1SMN1; SMN2KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025077311-A1 | METHOD FOR PREPARING MEDIUM- AND HIGH-VISCOSITY LUBRICANT BASE OILS | 中国石油天然气股份有限公司 | 2025-04-17 | — | — | WO | claimed |
| CN-119775463-A | Preparation method of medium-high viscosity lubricating oil base oil | 中国石油天然气股份有限公司 | 2025-04-08 | — | — | CN | claimed |
| CN-116554924-A | Preparation method of medium-high viscosity lubricating oil base oil | 中国石油天然气股份有限公司 | 2023-08-08 | — | — | CN | claimed |
| WO-2025077311-A1 | METHOD FOR PREPARING MEDIUM- AND HIGH-VISCOSITY LUBRICANT BASE OILS | 中国石油天然气股份有限公司 | 2025-04-17 | — | — | WO | disclosed |
| CN-119775463-A | Preparation method of medium-high viscosity lubricating oil base oil | 中国石油天然气股份有限公司 | 2025-04-08 | — | — | CN | disclosed |
| CN-116554924-A | Preparation method of medium-high viscosity lubricating oil base oil | 中国石油天然气股份有限公司 | 2023-08-08 | — | — | CN | disclosed |