Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26635234 | 0.71 | AKR1C3 (0.32) | — | |
| SCHEMBL14691566 | 0.67 | NFE2L2 (0.35) | ALDH1A1 | |
| SCHEMBL31711446 | 0.67 | CCR1 (0.36) | ALDH1A1 | |
| SCHEMBL29544937 | 0.67 | NFE2L2 (0.35) | ALDH1A1 | |
| SCHEMBL3368178 | 0.66 | NFE2L2 (0.33) | P2RX7 | |
| SCHEMBL5303261 | 0.66 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL30996264 | 0.66 | ALDH1A1 (0.40) | NPC1ALDH1A1MAPTHTTRAB9A | |
| SCHEMBL17979362 | 0.66 | TRPA1 (0.34) | ALDH1A1 | |
| SCHEMBL16635035 | 0.66 | TRPA1 (0.34) | ALDH1A1 | |
| SCHEMBL30540244 | 0.65 | XDH (0.46) | P2RX7ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116621778-A | USP inhibitor, preparation method and application thereof | 北京华森英诺生物科技有限公司 | 2023-08-22 | — | — | CN | disclosed |