Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | APEX1 | P27695 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1336721 | 0.84 | LMNA (0.42) | ALDH1A1MAPTSMN1; SMN2LMNAKDM4E | |
| SCHEMBL3044512 | 0.77 | PDE7A (0.37) | ALDH1A1MAPTSMN1; SMN2LMNAKDM4E | |
| SCHEMBL3838786 | 0.74 | PDE7A (0.35) | ALDH1A1MAPTSMN1; SMN2LMNAKDM4E | |
| SCHEMBL5833149 | 0.74 | PDE7A (0.56) | ALDH1A1MAPTALOX15SMN1; SMN2LMNA | |
| SCHEMBL28351783 | 0.74 | LMNA (0.46) | ALDH1A1MAPTSMN1; SMN2LMNAHPGD | |
| SCHEMBL8746025 | 0.74 | MAPT (0.37) | GPR35CTSBALDH1A1MAPTALOX15 | |
| SCHEMBL9635033 | 0.74 | APOBEC3G (0.55) | ALDH1A1MAPTSMN1; SMN2KDM4EHPGD | |
| SCHEMBL31163274 | 0.74 | POLB (0.59) | ALDH1A1MAPTALOX15SMN1; SMN2LMNA | |
| SCHEMBL2461047 | 0.74 | POLB (0.59) | ALDH1A1MAPTALOX15SMN1; SMN2LMNA | |
| SCHEMBL11554587 | 0.72 | SIRT1 (0.53) | ALDH1A1MAPTSMN1; SMN2KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6437178-B2 | REACTING A HALOGENATED BENZENE COMPOUND WITH NITRO(THIO)PHENOL; REDUCTION | INFINEON TECHNOLOGIES AG (DE) | 2002-08-20 | — | — | US | claimed |
| US-20010056203-A1 | O-aminophenolcarboxylic acid and o-aminothiophenolcarboxylic acid | SIEMENS AKTIENGESELLSCHAFT | 2001-12-27 | — | — | US | claimed |
| EP-0905124-B1 | o-amino(thio)phenol-carboxylic acids and their preparation | INFINEON TECHNOLOGIES AG (DE) | 2001-12-12 | — | — | EP | claimed |
| EP-0905123-B1 | o-amino(thio)phenol-carboxylic acids and their preparation | INFINEON TECHNOLOGIES AG (DE) | 2001-12-12 | — | — | EP | claimed |
| EP-0918050-B1 | Bis-o-amino(thio)phenols and their preparation | INFINEON TECHNOLOGIES AG (DE) | 2001-12-12 | — | — | EP | claimed |
| US-6096921-A | USED FOR THE PREPARATION OF HIGH-TEMPERATURE-STABLE POLYMERS, SUCH AS POLYBENZOXAZOLES AND POLYBENZTHIAZOLES | SIEMENS AKTIENGESELLSCHAFT (DE) | 2000-08-01 | — | — | US | claimed |
| EP-0918050-A1 | Bis-o-amino(thio)phenols and their preparation | SIEMENS AKTIENGESELLSCHAFT (DE) | 1999-05-26 | — | — | EP | claimed |
| EP-0905123-A1 | o-amino(thio)phenol-carboxylic acids and their preparation | SIEMENS AKTIENGESELLSCHAFT (DE) | 1999-03-31 | — | — | EP | claimed |
| EP-0905124-A1 | o-amino(thio)phenol-carboxylic acids and their preparation | SIEMENS AKTIENGESELLSCHAFT (DE) | 1999-03-31 | — | — | EP | claimed |
| JP-11158128-A | — | — | None | — | — | JP | disclosed |
| US-8431699-B2 | Method for manufacture of 2-oxoimidazolidines | Vertichem Corporation (CA) | 2013-04-30 | — | — | US | disclosed |
| WO-2010099518-A2 | METHOD FOR MANUFACTURE OF 2-OXOIMIDAZOLIDINES | THESIS CHEMISTRY, LLC (US) | 2010-09-02 | — | — | WO | disclosed |
| US-20100222588-A1 | Method for Manufacture of 2-Oxoimidazolidines | THESIS CHEMISTRY, LLC (US) | 2010-09-02 | — | — | US | disclosed |
| US-6627714-B2 | Copolymerizing ethylene and dicyclopentadiene or tricyclopentadiene, and cyclic olefin in presence of metallocene catalyst to produce copolymer | MARUZEN PETROCHEMICAL CO., LTD. (JP) | 2003-09-30 | — | — | US | disclosed |
| US-3987050-A | SUBSTITUTED PYRIDINYLALKOXY-, PYRIDINYLALKYLSULFONYL AND PYRIDINYLALKYLTHIO-PHENYL-LOWER-ALKANAMIDES | THE DOW CHEMICAL COMPANY (US) | 1976-10-19 | — | — | US | disclosed |
| US-3962265-A | H'-(4-((6-CHLORO-2-PYRIDINYL)OXY)PHENYL)-N-METHYL-N-(1-METHYL-2-PROPYNYL)UREA | THE DOW CHEMICAL COMPANY (US) | 1976-06-08 | — | — | US | disclosed |
| US-3947437-A | Substituted pyridazinyloxy(thio)phenyl ureas and derivatives thereof | THE DOW CHEMICAL COMPANY (US) | 1976-03-30 | — | — | US | disclosed |
| US-3940392-A | Certain pyrazinyloxyphenyl urea compound | THE DOW CHEMICAL COMPANY (US) | 1976-02-24 | — | — | US | disclosed |
| US-3931200-A | Substituted pyridinylalkoxy-, pyridinylalkylsulfonyl- and pyridinylalkylthio- phenylureas | THE DOW CHEMICAL COMPANY (US) | 1976-01-06 | — | — | US | disclosed |
| US-3931201-A | HERBICIDE | THE DOW CHEMICAL COMPANY (US) | 1976-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010056203-A1 | O-aminophenolcarboxylic acid and o-aminothiophenolcarboxylic acid | TPMT, PAH, AADAT | GPR35 2961/4885CTSB 3810/4885ALDH1A1 424/4885 |
| US-20100222588-A1 | Method for Manufacture of 2-Oxoimidazolidines | ODC1, CBR3, CBR1 | GPR35 3497/4885CTSB 2456/4885ALDH1A1 1602/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.