Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KDM4A | O75164 | 1/20 | 0.31 |
| ▸ | TDP2 | O95551 | 1/20 | 0.31 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1336721 | 0.84 | LMNA (0.42) | PDE7ASMN1; SMN2LMNAALDH1A1KMT2A | |
| SCHEMBL3044512 | 0.77 | PDE7A (0.37) | PDE7ASMN1; SMN2LMNAALDH1A1KMT2A | |
| SCHEMBL5833149 | 0.74 | PDE7A (0.56) | PDE7ASMN1; SMN2LMNAALDH1A1KMT2A | |
| SCHEMBL28351783 | 0.74 | LMNA (0.46) | PDE7ASMN1; SMN2LMNAALDH1A1KMT2A | |
| SCHEMBL3055047 | 0.74 | GPR35 (0.39) | PDE7ASMN1; SMN2LMNAALDH1A1KMT2A | |
| SCHEMBL9635033 | 0.69 | APOBEC3G (0.55) | SMN1; SMN2ALDH1A1KMT2AMAPTAPOBEC3G | |
| SCHEMBL31163274 | 0.69 | POLB (0.59) | SMN1; SMN2LMNAALDH1A1KMT2ATDP1 | |
| SCHEMBL2461047 | 0.69 | POLB (0.59) | SMN1; SMN2LMNAALDH1A1KMT2ATDP1 | |
| SCHEMBL4368894 | 0.69 | ALDH1A1 (0.53) | SMN1; SMN2ALDH1A1KMT2ATDP1PKM | |
| SCHEMBL11554587 | 0.68 | SIRT1 (0.53) | SMN1; SMN2ALDH1A1KMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017027062-A1 | PROBES FOR RAPID AND SPECIFIC DETECTION OF MYCOBACTERIA | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2017-02-16 | — | — | WO | disclosed |
| WO-2016210054-A1 | NOVEL RHODOL FLUOROPHORES FOR NEAR-INFRARED IMAGING | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2016-12-29 | — | — | WO | disclosed |
| EP-3094623-A1 | 6,7-TRANS CEPHALOSPORIN-BASED PROBES FOR DETECTING BACTERIA EXPRESSING A METALLO- -LACTAMASE | The Board of Trustees of The Leland Stanford Junior University (US) | 2016-11-23 | — | — | EP | disclosed |
| WO-2015109056-A1 | 6,7-TRANS CEPHALOSPORIN-BASED PROBES FOR DETECTING BACTERIA EXPRESSING A METALLO-β-LACTAMASE | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2015-07-23 | — | — | WO | disclosed |
| EP-1996175-A4 | A CYCLOHEXANE POLYALCOHOL FORMULATION FOR TREATMENT OF DISORDERS OF PROTEIN AGGREGATION | WARATAH PHARMACEUTICALS INC (CA) | 2009-06-10 | — | — | EP | disclosed |
| EP-2063894-A2 | FORMULATIONS CONTAINING PYRIDAZINE COMPOUNDS FOR TREATING NEUROINFLAMMATORY DISEASES | The Regents Of Northwestern University (US) | 2009-06-03 | — | — | EP | disclosed |
| EP-2015751-A2 | SALTS OF PYRIDAZINE COMPOUNDS | Northwestern University (US) | 2009-01-21 | — | — | EP | disclosed |
| EP-2015750-A2 | COMPOSITIONS AND TREATMENTS USING PYRIDAZINE COMPOUNDS AND CHOLINESTERASE INHIBITORS | Northwestern University (US) | 2009-01-21 | — | — | EP | disclosed |
| EP-1996175-A1 | A CYCLOHEXANE POLYALCOHOL FORMULATION FOR TREATMENT OF DISORDERS OF PROTEIN AGGREGATION | Waratah Pharmaceuticals, Inc. (CA) | 2008-12-03 | — | — | EP | disclosed |
| WO-2007130383-A2 | COMPOSITIONS AND TREATMENTS USING PYRIDAZINE COMPOUNDS AND SECRETASES | NORTHWESTERN UNIVERSITY (US) | 2007-11-15 | — | — | WO | disclosed |
| WO-2007127375-A2 | FORMULATIONS CONTAINING PYRIDAZINE COMPOUNDS FOR TREATING NEUROINFLAMMATORY DISEASES | NORTHWESTERN UNIVERSITY (US) | 2007-11-08 | — | — | WO | disclosed |
| WO-2007127475-A2 | PYRIDAZINES FOR DEMYELINATING DISEASES AND NEUROPATHIC PAIN | NORTHWESTERN UNIVERSITY (US) | 2007-11-08 | — | — | WO | disclosed |
| WO-2007127474-A2 | COMPOSITIONS AND TREATMENTS USING PYRIDAZINE COMPOUNDS AND CHOLINESTERASE INHIBITORS | NORTHWESTERN UNIVERSITY (US) | 2007-11-08 | — | — | WO | disclosed |
| WO-2007127448-A2 | SALTS OF PYRIDAZINE COMPOUNDS | NORTHWESTERN UNIVERSITY (US) | 2007-11-08 | — | — | WO | disclosed |
| WO-2007101353-A1 | A CYCLOHEXANE POLYALCOHOL FORMULATION FOR TREATMENT OF DISORDERS OF PROTEIN AGGREGATION | WARATAH PHARMACEUTICALS INC. (CA) | 2007-09-13 | — | — | WO | disclosed |